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[发病率登记中治疗进展的扩散研究。以卡尔瓦多斯省的直肠癌为例]

[Study of the diffusion of therapeutic progress in a morbidity register. Exemplified by rectal cancer in Calvados].

作者信息

Launoy G, Soumrany A, Pottier D, Gignoux M

机构信息

Calvados Faculté de Médecine CHRU Caen.

出版信息

Rev Epidemiol Sante Publique. 1991;39(6):523-9.

PMID:1796205
Abstract

Recent treatment trends have been studied among 614 rectal cancer cases collected in the Digestive Tract Cancer Registry in the "Département" of Calvados between 1978 and 1986. Of the 343 cases in which the tumour was resected, the sphincter was preserved in 32% of the cases (SP), and 30% had adjuvant radiotherapy (ART). The frequency of sphincter preservation (SP) and ART increased significantly during the study period. For both SP and ART, generalized use was less frequent and implemented later in unspecialized health care centres, even after adjustment for confounding. SP was more widely used in females and younger patients. Starting in 1984, the generalized use of ART - especially in pre-operative therapy - developed considerably, particularly for males and younger patients. Distance from the radiotherapy centre did not influence the radiotherapy rate. The use of morbidity registry data in assessing health care practices gives us a more precise view than hospital series, and provides information that can be extremely useful for formulating future guidelines for health care planning.

摘要

对1978年至1986年间在卡尔瓦多斯省消化道癌症登记处收集的614例直肠癌病例的近期治疗趋势进行了研究。在343例肿瘤被切除的病例中,32%的病例保留了括约肌(SP),30%的病例接受了辅助放疗(ART)。在研究期间,括约肌保留(SP)和ART的频率显著增加。对于SP和ART,在非专科医疗中心,普遍使用的频率较低且实施较晚,即使在对混杂因素进行调整之后也是如此。SP在女性和年轻患者中使用更为广泛。从1984年开始,ART的普遍使用——尤其是在术前治疗中——有了显著发展,特别是在男性和年轻患者中。与放疗中心的距离并未影响放疗率。利用发病率登记数据评估医疗实践,比医院系列数据能让我们有更精确的认识,并提供对制定未来医疗规划指南极为有用的信息。

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