圆锥角膜经核黄素和紫外线A角膜交联术后发生的疱疹性角膜炎伴虹膜炎。
Herpetic keratitis with iritis after corneal crosslinking with riboflavin and ultraviolet A for keratoconus.
作者信息
Kymionis George D, Portaliou Dimitra M, Bouzoukis Dimitrios I, Suh Leejee H, Pallikaris Aristofanis I, Markomanolakis Marinos, Yoo Sonia H
机构信息
Department of Ophthalmology, University of Crete, Crete, Greece.
出版信息
J Cataract Refract Surg. 2007 Nov;33(11):1982-4. doi: 10.1016/j.jcrs.2007.06.036.
A 21-year-old woman had crosslinking for keratoconus in the right eye; the left eye was scheduled for penetrating keratoplasty. Five days postoperatively, she presented with geographic epithelial keratitis and iritis. Analysis of tear samples by polymerase chain reaction confirmed the diagnosis. The patient was treated with oral steroids and acyclovir, with significant improvement. Two months postoperatively, the visual acuity was improved and there was no evidence of herpetic disease recurrence. Crosslinking can induce herpetic keratitis with iritis even in patients with no history of herpetic disease. Early diagnosis and proper treatment are essential for a favorable outcome.
一名21岁女性右眼因圆锥角膜接受了交联手术；左眼计划进行穿透性角膜移植术。术后五天，她出现了地图状上皮性角膜炎和虹膜炎。通过聚合酶链反应对泪液样本进行分析确诊了病情。患者接受了口服类固醇和阿昔洛韦治疗，病情有显著改善。术后两个月，视力有所提高，且没有疱疹性疾病复发的迹象。即使是没有疱疹性疾病病史的患者，交联手术也可能诱发伴有虹膜炎的疱疹性角膜炎。早期诊断和恰当治疗对于取得良好疗效至关重要。
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