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一例表现为多种血栓栓塞现象的围产期心肌病的罕见病例。

An unusual case of peripartum cardiomyopathy manifesting with multiple thrombo-embolic phenomena.

机构信息

Division of Cardiology, Medical College of Georgia, Augusta, Georgia, USA.

出版信息

Thromb J. 2007 Oct 29;5:18. doi: 10.1186/1477-9560-5-18.

Abstract

Peripartum cardiomyopathy (PPCM) is a rare form of heart failure with a reported incidence of 1 per 3000 to 1 per 4000 live births and a fatality rate of 20%-50%. Onset is usually between the last month of pregnancy and up to 5 months postpartum in previously healthy women. Although viral, autoimmune and idiopathic factors may be contributory, its etiology remains unknown. PPCM initially presents with signs and symptoms of congestive heart failure and rarely with thrombo-embolic complications. We report an unusual case of PPCM in a previously healthy postpartum woman who presented with an acute abdomen due to unrecognized thromboemboli of the abdominal organs. This case illustrates that abdominal pain in PPCM may not always result from hepatic congestion as previously reported, but may occur as a result of thromboemboli to abdominal organs. Further research is needed to determine the true incidence of thromboemboli in PPCM.

摘要

围生期心肌病(PPCM)是一种罕见的心力衰竭形式,据报道发病率为每 3000 至 4000 例活产 1 例,死亡率为 20%-50%。通常在健康妇女妊娠的最后一个月至产后 5 个月内发病。虽然病毒、自身免疫和特发性因素可能起作用,但病因仍不清楚。PPCM 最初表现为充血性心力衰竭的体征和症状,很少出现血栓栓塞并发症。我们报告了一例先前健康的产后妇女发生 PPCM 的不寻常病例,该患者因腹部器官未被识别的血栓栓塞而出现急性腹痛。本例说明,PPCM 中的腹痛并不总是如先前报道的那样由于肝充血引起,也可能是由于腹部器官的血栓栓塞引起。需要进一步研究以确定 PPCM 中血栓栓塞的真实发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea22/2169208/4eccab5787ee/1477-9560-5-18-1.jpg

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