Dewey Marc, Schink Tania, Dewey Charles F
Department of Radiology, Charité, Medical School, Humboldt-Universität zu Berlin, Berlin, Germany.
J Magn Reson Imaging. 2007 Nov;26(5):1322-7. doi: 10.1002/jmri.21147.
To evaluate whether MR scanners with acoustic noise reduction and a short magnetic bore reduce the rate of claustrophobic reactions.
We performed a cohort study in an outpatient setting, enrolling a total of 55,734 consecutive patients referred for MRI of any part of the body based on a clinical indication. Imaging was performed using a conventional MR scanner (42,998 patients) and a recently developed MR scanner (12,736 patients) with 97% acoustic noise reduction and a short bore. Multiple logistic regression analysis was used to adjust for the nonrandomized design.
In addition to those undergoing head-first examinations, female and middle-aged patients were significantly more likely to develop claustrophobia in the logistic regression analysis (P < 0.001). The rate of claustrophobic reactions was significantly lower with the recent MR scanner (0.7%; 95% confidence interval [CI]: 0.6-0.9%) than with the conventional scanner (2.1%; 95% CI, 2.0-2.3%; P < 0.001) with an adjusted odds ratio (OR) of 3.1 (95% CI, 2.5-3.9) and a number needed to treat of 72 (95% CI, 63-85).
The incidence of claustrophobia may be reduced by a factor of 3 when recently-developed MR scanners are used.
评估具有降噪功能和短磁体孔径的磁共振成像（MR）扫描仪是否能降低幽闭恐惧症反应的发生率。
我们在门诊环境中进行了一项队列研究，纳入了总共55734例因临床指征而被转诊至全身任何部位进行磁共振成像检查的连续患者。成像检查使用了一台传统MR扫描仪（42998例患者）和一台最近研发的MR扫描仪（12736例患者），后者具有97%的降噪功能和短磁体孔径。采用多因素logistic回归分析对非随机设计进行校正。
在logistic回归分析中，除了头先进检查的患者外，女性和中年患者发生幽闭恐惧症的可能性显著更高（P<0.001）。与传统扫描仪（2.1%；95%置信区间[CI]：2.0-2.3%）相比，最近研发的MR扫描仪的幽闭恐惧症反应发生率显著更低（0.7%；95%CI：0.6-0.9%；P<0.001），校正后的比值比（OR）为3.1（95%CI：2.5-3.9），需治疗人数为72（95%CI：63-85）。
使用最近研发的MR扫描仪时，幽闭恐惧症的发生率可能降低3倍。
