Otawara Yasunari, Ogasawara Kuniaki, Kubo Yoshitaka, Sasoh Masayuki, Ogawa Akira
Department of Neurosurgery, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate 020-8505, Japan.
Vasc Health Risk Manag. 2007;3(4):401-4.
External cerebrospinal fluid (CSF) drainage is an effective method to remove massive subarachnoid hemorrhage (SAH), but carries the risk of meningitis and shunt-dependent hydrocephalus. This study investigated whether postoperative cisternal CSF drainage affects the incidence of cerebral vasospasm and clinical outcome in patients with thin SAH. Seventy-eight patients with thin SAH, 22 men and 56 women aged from 17 to 73 years (mean 51.2 years), underwent surgical repair for ruptured anterior circulation aneurysm. Patients were divided into groups with (38 patients) and without (40 patients) postoperative cisternal CSF drainage, and the incidences of angiographical and symptomatic vasospasm, shunt-dependent hydrocephalus, meningitis, and the clinical outcome were compared. The incidences of angiographical vasospasm (31.6% vs 50.0%), symptomatic vasospasm (7.9% vs 12.5%), shunt-dependent hydrocephalus (5.3% vs 0%), and meningitis (2.6% vs 0%) did not differ between patients with and without cisternal CSF drainage. All patients in both groups resulted in good recovery. Postoperative cisternal CSF drainage does not affect the incidence of cerebral vasospasm or the clinical outcome in patients with thin SAH.
脑室外引流是清除大量蛛网膜下腔出血(SAH)的有效方法,但存在脑膜炎和分流依赖性脑积水的风险。本研究调查了术后脑池脑脊液引流是否会影响薄SAH患者脑血管痉挛的发生率和临床结局。78例薄SAH患者,男22例,女56例,年龄17至73岁(平均51.2岁),因前循环动脉瘤破裂接受手术修复。患者分为术后行脑池脑脊液引流组(38例)和未行脑池脑脊液引流组(40例),比较两组血管造影性和症状性血管痉挛、分流依赖性脑积水、脑膜炎的发生率以及临床结局。脑池脑脊液引流组和未引流组患者的血管造影性血管痉挛发生率(31.6%对50.0%)、症状性血管痉挛发生率(7.9%对12.5%)、分流依赖性脑积水发生率(5.3%对0%)和脑膜炎发生率(2.6%对0%)无差异。两组所有患者均恢复良好。术后脑池脑脊液引流不影响薄SAH患者脑血管痉挛的发生率或临床结局。