Tropskaya N S, Solov'yova G I, Popova T S
N. V. Sklifosovsky Institute of Urgent Care, Moscow.
Bull Exp Biol Med. 2007 Feb;143(2):194-6. doi: 10.1007/s10517-007-0048-4.
The effects of neostigmine and calcium pantothenate on electrical activity of the stomach and small intestine were studied in chronic experiments on rats after laparotomy with implantation of a probe into the jejunum and electrodes into different portions of the gastrointestinal tract. At the early terms after surgery, stimulation of endogenous acetylcholine release intensified electrical activity of the stomach, duodenum, and jejunum. Treatment with neostigmine and calcium pantothenate did not accelerate the recovery of the migrating myoelectrical complex, but promoted the recovery of the general intensity of action potential generation in the stomach and small intestine.
在对大鼠进行剖腹手术并将探头植入空肠、电极植入胃肠道不同部位的慢性实验中，研究了新斯的明和泛酸钙对胃和小肠电活动的影响。在术后早期，刺激内源性乙酰胆碱释放可增强胃、十二指肠和空肠的电活动。新斯的明和泛酸钙治疗并未加速移行性肌电复合波的恢复，但促进了胃和小肠动作电位产生总体强度的恢复。
