钴催化的炔基格氏试剂与烯基三氟甲磺酸酯的交叉偶联反应。
Cobalt-catalyzed cross-coupling of alkynyl Grignard reagents with alkenyl triflates.
作者信息
Shirakawa Eiji, Sato Takahiro, Imazaki Yusuke, Kimura Takahiro, Hayashi Tamio
机构信息
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.
出版信息
Chem Commun (Camb). 2007 Nov 21(43):4513-5. doi: 10.1039/b711884h. Epub 2007 Aug 28.
DOI:10.1039/b711884h
PMID:17971973
Abstract
Alkenyl triflates in combination with Co(acac)(3) as a catalyst were found to be excellent coupling partners of alkynyl Grignard reagents, where no special additives (even a phosphine ligand) but a common solvent, THF, are required to obtain variously substituted enynes.
摘要
已发现烯基三氟甲磺酸酯与作为催化剂的三乙酰丙酮钴（III）相结合时，是炔基格氏试剂的优良偶联伙伴，在此反应中，无需特殊添加剂（甚至膦配体），仅需常用溶剂四氢呋喃（THF）就能得到各种取代的烯炔。
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