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用于通过电感耦合等离子体质谱法（ICP-MS）增强检测的核酸纳米颗粒标记

Nano-particle labelling of nucleic acids for enhanced detection by inductively-coupled plasma mass spectrometry (ICP-MS).

作者信息

Kerr Samantha Louise, Sharp Barry

机构信息

Department of Chemistry, Loughborough University, Loughborough, Leicestershire, UK LE11 3TU.

出版信息

Chem Commun (Camb). 2007 Nov 21(43):4537-9. doi: 10.1039/b709466c. Epub 2007 Sep 14.

DOI:10.1039/b709466c
PMID:17971981
Abstract

Oligonucleotides containing a biotin functionality were successfully labelled with a streptavidin nanogold conjugate and subsequently separated and analysed by high performance liquid chromatography-inductively coupled plasma-mass spectrometry (HPLC-ICP-MS).

摘要

含有生物素功能的寡核苷酸已成功地用链霉亲和素纳米金共轭物标记，随后通过高效液相色谱-电感耦合等离子体质谱法（HPLC-ICP-MS）进行分离和分析。

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