Feng Hsu Shao, Pinheiro Isabella Cristina Mendes, Grande Sabrina Rosa, Pannuti Cláudio Mendes, Barros Fernando José Nunes, Lotufo Roberto Fraga Moreira
University of São Paulo, Brazil.
Spec Care Dentist. 2007 Jul-Aug;27(4):144-8. doi: 10.1111/j.1754-4505.2007.tb00337.x.
This randomized clinical trial investigated the effect of a dentifrice containing triclosan on the reduction of dental plaque and gingivitis in institutionalized individuals with cerebral palsy. Fifty-seven residents were randomly allocated to a test group (n=28, dentifrice with triclosan) and a control group (n=29, conventional dentifrice). A single calibrated investigator performed examinations at baseline and after three months. The amount of dental plaque was assessed, and gingivitis was measured. The caretakers performed brushing with dentifrice. After three months, there was a significant reduction in the plaque index in both groups, but there was no difference between the two groups. There was a significant reduction in gingivitis only in the test group, and the difference between groups was significant after three months. The authors concluded that the dentifrice with triclosan reduced interdental bleeding in the studied population.
这项随机临床试验研究了含三氯生牙膏对减少脑瘫机构化个体牙菌斑和牙龈炎的效果。57名居民被随机分配到试验组（n = 28，含三氯生牙膏）和对照组（n = 29，传统牙膏）。由一名经过校准的调查员在基线和三个月后进行检查。评估牙菌斑量并测量牙龈炎情况。护理人员用牙膏进行刷牙。三个月后，两组的菌斑指数均显著降低，但两组之间无差异。仅试验组的牙龈炎有显著降低，且三个月后两组间差异显著。作者得出结论，含三氯生牙膏减少了研究人群的牙间出血。
