Nowicka Urszula, Wiatr Elzbieta, Kupis Włodzimierz, Burakowska Barbara, Folcik Krystyna, Orłowski Tadeusz, Roszkowski-Sliz Kazimierz
Instytut Gruźlicy i Chorób Płuc w Warszawie.
Pneumonol Alergol Pol. 2007;75(2):200-7.
Hyper IgE syndrome (Job's syndrome) is a rare multiorgan disease characterized by the triad: elevated serum IgE level, recurrent sinopulmonary infections, most often staphylococcal, and cutaneous cold abscesses starting in infancy. We report 21 years old patient with hyper IgE syndrome, diagnosed at age of 6 years on the basis of hyperimmunoglobulinaemia E and recurrent pulmonary and cutaneous infections. Now he was admitted because of pneumonia complicating with pneumatocele, which could not be resolved despite intravenous antibiotics. Surgical intervention was necessary. The postoperative period was complicated by Staphyloccocus aureus sepsis.
高免疫球蛋白E综合征（乔布综合征）是一种罕见的多器官疾病，其特征为三联征：血清IgE水平升高、反复的鼻窦肺部感染（最常见为葡萄球菌感染）以及自婴儿期起出现的皮肤冷脓肿。我们报告一名21岁的高免疫球蛋白E综合征患者，他在6岁时因高免疫球蛋白血症E以及反复的肺部和皮肤感染而被诊断。现因肺炎并发肺气囊入院，尽管使用了静脉抗生素治疗，但仍无法缓解。手术干预是必要的。术后出现了金黄色葡萄球菌败血症并发症。
