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成人高免疫球蛋白E与反复感染综合征

The hyperimmunoglobulinaemia E and recurrent infections syndrome in an adult.

作者信息

L'Huillier J P, Thoreux P H, Delaval P, Desrues B, Le Gall E, Kernec J, Delambre J F

机构信息

Service de Pneumologie, Centre Hospitalier Régional et Universitaire, Rennes, France.

出版信息

Thorax. 1990 Sep;45(9):707-8. doi: 10.1136/thx.45.9.707.

DOI:10.1136/thx.45.9.707
PMID:2218977
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC462705/
Abstract

A 27 year old white woman with a history of chronic eczema and episodes of serious infection of the chest, skin, and bone presented with acute respiratory failure. She was found to have a spontaneous right pneumothorax and a pneumatocele in the left upper lobe. Despite a left upper lobectomy she was left with chronic respiratory failure, bullous lung disease, and bilateral bronchiectasis. The hyperimmunoglobulinaemia E and recurrent infections syndrome was diagnosed only in adult life.

摘要

一名27岁的白人女性,有慢性湿疹病史,曾出现胸部、皮肤和骨骼的严重感染,此次因急性呼吸衰竭就诊。检查发现她有自发性右侧气胸和左上叶肺气囊。尽管接受了左上叶切除术,但她仍患有慢性呼吸衰竭、大疱性肺病和双侧支气管扩张。高免疫球蛋白E和反复感染综合征直到成年才被诊断出来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cabd/462705/a085b51fc9ca/thorax00345-0062-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cabd/462705/16729cd05a07/thorax00345-0061-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cabd/462705/a085b51fc9ca/thorax00345-0062-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cabd/462705/16729cd05a07/thorax00345-0061-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cabd/462705/a085b51fc9ca/thorax00345-0062-a.jpg

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本文引用的文献

1
[Susceptibility to infections and hyper IgE: 19 new case reports ].[感染易感性与高免疫球蛋白E:19例新病例报告]
Arch Fr Pediatr. 1982 Jun-Jul;39(6):353-8.
2
The syndrome of hyperimmunoglobulinemia E and recurrent infections.高免疫球蛋白E综合征与反复感染
Am J Dis Child. 1982 Sep;136(9):767-71. doi: 10.1001/archpedi.1982.03970450009001.
3
[Secondarily infected pneumatocele, eosinophilia and excess production of IgE manifesting as Buckley's syndrome in an adult].[成人继发性感染性肺大疱、嗜酸性粒细胞增多及IgE过度产生,表现为巴克利综合征]
Poumon Coeur. 1983;39(2):95-100.
4
Deficiency of suppressor T cells in the hyperimmunoglobulin E syndrome.高免疫球蛋白E综合征中抑制性T细胞的缺乏。
J Clin Invest. 1981 Sep;68(3):783-91. doi: 10.1172/jci110315.
5
[A syndrome of hyper-IgE and recurrent infections. Developmental variants? A familial study].[高IgE与反复感染综合征。发育变异?一项家族性研究]
Ann Dermatol Venereol. 1984;111(1):39-46.
6
Extreme hyperimmunoglobulinemia E and undue susceptibility to infection.极高的免疫球蛋白E血症与过度易感性感染。
Pediatrics. 1972 Jan;49(1):59-70.
7
Job's Syndrome. Recurrent, "cold", staphylococcal abscesses.乔布综合征。复发性“冷性”葡萄球菌脓肿。
Lancet. 1966 May 7;1(7445):1013-5. doi: 10.1016/s0140-6736(66)90119-x.
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Hyperimmunoglobulinemia E syndrome: pulmonary imaging considerations.高免疫球蛋白E综合征:肺部影像学考量
Pediatr Radiol. 1986;16(4):285-8. doi: 10.1007/BF02386863.
9
Abnormalities in the regulation of human IgE synthesis.人类IgE合成调节异常。
Immunol Rev. 1978;41:288-314. doi: 10.1111/j.1600-065x.1978.tb01469.x.