手性硫醇：通过¹H NMR确定其绝对构型

Chiral thiols: the assignment of their absolute configuration by 1H NMR.

作者信息

Porto Silvia, Seco José Manuel, Ortiz Aurelio, Quiñoá Emilio, Riguera Ricardo

机构信息

Departamento de Química Orgánica, Facultad de Química y Unidad de RMN de Biomoléculas Asociada al CSIC, Universidad de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.

出版信息

Org Lett. 2007 Nov 22;9(24):5015-8. doi: 10.1021/ol7022196. Epub 2007 Oct 31.

DOI:10.1021/ol7022196

PMID:17973398

Abstract

A general NMR spectroscopy protocol for determination of absolute configuration of thiols, that includes the introduction of new aryl-tert-butoxyacetic acids as chiral derivatizing agents (CDAs), is described.

摘要

本文描述了一种用于测定硫醇绝对构型的通用核磁共振光谱法，该方法包括引入新型芳基叔丁氧基乙酸作为手性衍生化试剂（CDA）。