Billaud-Debarre C, Alibeu J P, Arvieux C C, Fargnoli J M, Plantaz D
Département d'Anesthésiologie, CHRU Grenoble.
Cah Anesthesiol. 1991;39(7):461-4.
The authors have studied a population of 51 children in which 63 central venous catheters were used for the treatment of leukemias, solid tumors and lymphomas. Two groups were isolated: continuous hospitalization (group A) and intermittent hospitalization with periodical day care (group B). Mean duration of catheterization was 129 days in group A and 176 days in group B (whole population: 149 days), with a total of 9,724 days of catheterization. There was no significant differences between the two groups concerning infection, bleeding, thrombosis or migration. So the authors believe that permanent hospitalization is not mandatory for chemotherapy in children with severe malignant diseases. Periodical day care therapy allows a near normal life for children and a better cooperation from their parents.
作者对51名儿童进行了研究，这些儿童共使用了63根中心静脉导管来治疗白血病、实体瘤和淋巴瘤。分为两组：持续住院（A组）和定期日间护理的间歇性住院（B组）。A组导管插入的平均持续时间为129天，B组为176天（总体人群：149天），导管插入总天数为9724天。两组在感染、出血、血栓形成或移位方面无显著差异。因此，作者认为，患有严重恶性疾病的儿童化疗并非必须持续住院。定期日间护理疗法能让儿童的生活接近正常，且能让其父母更好地配合。
