类风湿关节炎中的皮肤肉芽肿。

Cutaneous granulomas in rheumatoid arthritis.

作者信息

Collaris Esther J H, van Marion Ariënne M W, Frank Jorge, Poblete-Gutiérrez Pamela

机构信息

Department of Dermatology, University Hospital Maastricht, The Netherlands.

出版信息

Int J Dermatol. 2007 Nov;46 Suppl 3:33-5. doi: 10.1111/j.1365-4632.2007.03509.x.

DOI:10.1111/j.1365-4632.2007.03509.x

PMID:17973887

Abstract

A 57-year-old man with rheumatoid arthritis and myasthenia gravis developed an asymptomatic erythematous plaque on his nose and skin-colored nodules on the elbows. Histopathological examination was suggestive of palisaded neutrophilic granulomatous dermatitis (PNGD). PNGD is a rather uncommon cutaneous finding in different collagen vascular disorders that can manifest with a broad range of clinical symptoms and histological signs. Based on the case report of the patient described here, we briefly discuss what is currently known about this disease.

摘要

一名患有类风湿性关节炎和重症肌无力的57岁男性，鼻子上出现了无症状的红斑性斑块，肘部出现了肤色结节。组织病理学检查提示为栅栏状中性粒细胞肉芽肿性皮炎（PNGD）。PNGD是一种在不同胶原血管疾病中较为罕见的皮肤表现，可呈现出广泛的临床症状和组织学特征。基于此处所述患者的病例报告，我们简要讨论一下目前对该疾病的了解。