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类风湿关节炎中的皮肤肉芽肿。

Cutaneous granulomas in rheumatoid arthritis.

作者信息

Collaris Esther J H, van Marion Ariënne M W, Frank Jorge, Poblete-Gutiérrez Pamela

机构信息

Department of Dermatology, University Hospital Maastricht, The Netherlands.

出版信息

Int J Dermatol. 2007 Nov;46 Suppl 3:33-5. doi: 10.1111/j.1365-4632.2007.03509.x.

DOI:10.1111/j.1365-4632.2007.03509.x
PMID:17973887
Abstract

A 57-year-old man with rheumatoid arthritis and myasthenia gravis developed an asymptomatic erythematous plaque on his nose and skin-colored nodules on the elbows. Histopathological examination was suggestive of palisaded neutrophilic granulomatous dermatitis (PNGD). PNGD is a rather uncommon cutaneous finding in different collagen vascular disorders that can manifest with a broad range of clinical symptoms and histological signs. Based on the case report of the patient described here, we briefly discuss what is currently known about this disease.

摘要

一名患有类风湿性关节炎和重症肌无力的57岁男性,鼻子上出现了无症状的红斑性斑块,肘部出现了肤色结节。组织病理学检查提示为栅栏状中性粒细胞肉芽肿性皮炎(PNGD)。PNGD是一种在不同胶原血管疾病中较为罕见的皮肤表现,可呈现出广泛的临床症状和组织学特征。基于此处所述患者的病例报告,我们简要讨论一下目前对该疾病的了解。

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1
Cutaneous granulomas in rheumatoid arthritis.类风湿关节炎中的皮肤肉芽肿。
Int J Dermatol. 2007 Nov;46 Suppl 3:33-5. doi: 10.1111/j.1365-4632.2007.03509.x.
2
The histopathologic spectrum of palisaded neutrophilic and granulomatous dermatitis in patients with collagen vascular disease.胶原血管病患者栅栏状中性粒细胞和肉芽肿性皮炎的组织病理学谱。
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Palisaded neutrophilic granulomatous dermatitis in rheumatoid arthritis.类风湿关节炎中的栅栏状中性粒细胞肉芽肿性皮炎
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Palisaded neutrophilic granulomatous dermatitis with leukocytoclastic vasculitis in a patient without any underlying systemic disease detected to date.在一名迄今为止未检测到任何潜在全身性疾病的患者中出现的伴有白细胞破碎性血管炎的栅栏状嗜中性粒细胞肉芽肿性皮炎。
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Granulomatous cutaneous rheumatoid vasculitis.肉芽肿性皮肤类风湿性血管炎
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Palisaded neutrophilic and granulomatous dermatitis presenting in a patient with rheumatoid arthritis on adalimumab.在使用阿达木单抗治疗的类风湿关节炎患者中出现的栅栏状中性粒细胞和肉芽肿性皮炎。
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