从犬的耳部和皮肤分离出的假单胞菌对恩诺沙星、马波沙星和环丙沙星的敏感性。

Susceptibility of Pseudomonas isolates from the ears and skin of dogs to enrofloxacin, marbofloxacin, and ciprofloxacin.

作者信息

Wildermuth Brett Everett, Griffin Craig E, Rosenkrantz Wayne S, Boord Mona J

机构信息

Animal Dermatology Clinic, 5610 Kearny Mesa Road, Suite B1, San Diego, California 92111, USA.

出版信息

J Am Anim Hosp Assoc. 2007 Nov-Dec;43(6):337-41. doi: 10.5326/0430337.

DOI:10.5326/0430337

PMID:17975216

Abstract

The purpose of this study was to compare susceptibilities of ear and skin Pseudomonas spp. isolates to enrofloxacin, marbofloxacin, and ciprofloxacin. Specimens were obtained from dogs examined in a veterinary dermatology referral hospital. Susceptibilities of ear isolates to enrofloxacin, marbofloxacin, and ciprofloxacin were 46.9%, 66.7%, and 75.0%, respectively. Susceptibilities of skin isolates to the same drugs were 76.2%, 81.0%, and 80.0%, respectively. Ear isolates were significantly less susceptible to enrofloxacin than to ciprofloxacin (P=0.021), and ear isolates were significantly less susceptible to enrofloxacin than were skin isolates (P=0.034). When fluoroquinolone resistance was present, ear isolates were significantly less susceptible to enrofloxacin than to ciprofloxacin (P<0.001) and marbofloxacin (P=0.014).

摘要

本研究的目的是比较耳部和皮肤分离的假单胞菌属菌株对恩诺沙星、马波沙星和环丙沙星的敏感性。样本取自一家兽医皮肤科转诊医院检查的犬只。耳部分离菌株对恩诺沙星、马波沙星和环丙沙星的敏感性分别为46.9%、66.7%和75.0%。皮肤分离菌株对相同药物的敏感性分别为76.2%、81.0%和80.0%。耳部分离菌株对恩诺沙星的敏感性显著低于对环丙沙星的敏感性（P=0.021），且耳部分离菌株对恩诺沙星的敏感性显著低于皮肤分离菌株（P=0.034）。当存在氟喹诺酮耐药性时，耳部分离菌株对恩诺沙星的敏感性显著低于对环丙沙星的敏感性（P<0.001）和马波沙星的敏感性（P=0.014）。