Dégi János, Moțco Oana-Alexandra, Dégi Diana Maria, Suici Tiana, Mareș Mihai, Imre Kalman, Cristina Romeo Teodor
Department of Infectious Diseases and Preventive Medicine, Faculty of Veterinary Medicine, Banat's University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara, 300645 Timisoara, Romania.
Dialab Solutions, 011607 Bucharest, Romania.
Antibiotics (Basel). 2021 Jul 12;10(7):846. doi: 10.3390/antibiotics10070846.
Treating infections caused by is increasingly difficult due to high antibiotic resistance, materialized through the presence of multiple resistance strains, as well as due to rapid development of resistance throughout treatment. The present survey was conducted to investigate the antibiotic susceptibility profile of pathogens in two University Veterinary hospitals from different geographical regions of Romania (i.e., Southwest Timișoara county and Northeast Iași county) involved in superficial canine infections. A total of 142 swab specimens were collected from dogs with superficial infections (superficial skin infections, otitis externa, and perianal abscess) to assess the presence of , based on phenotypic and molecular characterization. According to their confirmed morphological and molecular features, 58 samples (40.84%; 58/142) were positive for (according to their confirmed morphological and molecular features). Antibiotic susceptibility testing for 12 antibiotics was conducted using the Kirby-Bauer disc diffusion method. Drug resistance was observed in the case of all tested antibiotics. The susceptibility rate of strains that were tested in this study was in the following order: ceftazidime (53.44%; 31/58), followed by aztreonam (51.72%; 30/58), amikacin (44.82%; 26/58), azithromycin (41.37%; 24/58), gentamicin (37.93%; 22/58), cefepime (36.20%; 21/58), meropenem (25.86%; 13/58), piperacillin-tazobactam (25.86%; 13/58), imipenem (22.41%; 13/158), ciprofloxacin (17.24%; 10/58), tobramycin (8.62; 5/58), and polymyxin B (1.72; 1/58). The results highlight the importance of antibiotic susceptibility testing in isolates from dogs with superficial infections to use an adequate treatment plan to manage the skin condition and other pathologies (otitis externa and perianal abscesses).
由于多重耐药菌株的存在导致抗生素耐药性高，以及在整个治疗过程中耐药性的快速发展，治疗由……引起的感染变得越来越困难。本次调查旨在研究罗马尼亚不同地理区域（即西南部的蒂米什瓦拉县和东北部的雅西县）两家大学兽医医院中涉及犬浅表感染的……病原体的抗生素敏感性概况。总共从患有浅表感染（浅表皮肤感染、外耳道炎和肛周脓肿）的犬只中采集了142份拭子标本，基于表型和分子特征评估……的存在情况。根据其已确认的形态和分子特征，58份样本（40.84%；58/142）对……呈阳性（根据其已确认的形态和分子特征）。使用 Kirby-Bauer 纸片扩散法对12种抗生素进行了药敏试验。在所有测试抗生素的情况下均观察到耐药性。本研究中测试的……菌株的药敏率顺序如下：头孢他啶（53.44%；31/58），其次是氨曲南（51.72%；30/58）、阿米卡星（44.82%；26/58）、阿奇霉素（41.37%；24/58）、庆大霉素（37.93%；22/58）、头孢吡肟（36.20%；21/58）、美罗培南（25.86%；13/58）、哌拉西林 - 他唑巴坦（25.86%；13/58）、亚胺培南（22.41%；13/58）、环丙沙星（17.24%；10/58）、妥布霉素（8.62%；5/58）和多粘菌素B（1.72%；1/58）。结果突出了对患有浅表感染的犬只的……分离株进行药敏试验对于制定适当治疗方案以管理皮肤状况和其他病症（外耳道炎和肛周脓肿）的重要性。
