Hussain M A, Ali E M, Ahmed H S
Department of Paediatrics, Faculty of Medicine, University of Khartoum, Sudan.
East Afr Med J. 1991 Sep;68(9):679-85.
Two hundred Sudanese children (105 males, 95 females) with otitis media (OM) were studied. Their age range was from 3 months to 15 years, with 41.5% being below 2 years of age. The presenting symptoms included ear discharge in 96% and pyrexia in 26.5% of patients. Ear ache and itching were reported in 22.5% and 7.0% respectively and impaired hearing in 7.0%. Bacterial pathogens were isolated from 115 (70.1%) of 164 cultures from children with chronic discharging ears. Organisms isolated in order of frequency were: Proteus species, Klebsiella with other coliforms, Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Sixty of 84 (71.4%) cultures from children with acute OM grew pathogenic bacteria. Staphylococcus aureus and Klebsiella with other coliforms were the commonest pathogens. Proteus species and Pseudomonas aeruginosa were less frequent but beta-haemolytic Streptococcus, Streptococcus pneumoniae and Escherichia coli were the least common. Antibiotic sensitivity results show that the majority of isolates from children with discharging ears were sensitive to Gentamicin, followed by Co-trimoxazole and Streptomycin. The majority of organisms showed poor sensitivity to Ampicillin and Penicillin. The results of this study show that cotrimoxazole is the drug of choice for treating children with OM.
对200名患有中耳炎(OM)的苏丹儿童(105名男性,95名女性)进行了研究。他们的年龄范围为3个月至15岁,其中41.5%的儿童年龄在2岁以下。出现的症状包括96%的患者有耳漏,26.5%的患者有发热。分别有22.5%和7.0%的患者报告有耳痛和瘙痒,7.0%的患者有听力受损。从164例慢性耳漏儿童的培养物中,有115例(70.1%)分离出细菌病原体。按频率顺序分离出的微生物为:变形杆菌属、克雷伯菌属及其他大肠菌群、金黄色葡萄球菌、铜绿假单胞菌和大肠杆菌。84例急性中耳炎儿童的培养物中有60例(71.4%)培养出病原菌。金黄色葡萄球菌和克雷伯菌属及其他大肠菌群是最常见的病原体。变形杆菌属和铜绿假单胞菌较少见,但β-溶血性链球菌、肺炎链球菌和大肠杆菌最不常见。抗生素敏感性结果显示,耳漏儿童分离出的大多数菌株对庆大霉素敏感,其次是复方新诺明和链霉素。大多数微生物对氨苄西林和青霉素敏感性较差。本研究结果表明,复方新诺明是治疗中耳炎儿童的首选药物。