Suppr超能文献

一家小动物重症监护病房耐甲氧西林金黄色葡萄球菌定植群

Cluster of methicillin-resistant Staphylococcus aureus colonization in a small animal intensive care unit.

作者信息

Weese J Scott, Faires Meredith, Rousseau Joyce, Bersenas Alexa M E, Mathews Karol A

机构信息

Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada.

出版信息

J Am Vet Med Assoc. 2007 Nov 1;231(9):1361-4. doi: 10.2460/javma.231.9.1361.

Abstract

CASE DESCRIPTION

Methicillin-resistant Staphylococcus aureus (MRSA) was isolated from the tracheostomy tube of an 18-month-old castrated male Golden Retriever in the intensive care unit (ICU) of the Ontario Veterinary College. This prompted an investigation of MRSA colonization in other animals in the ICU.

CLINICAL FINDINGS

On day 1 of the investigation, MRSA was isolated from nasal swabs obtained from 2 of 10 animals (2/7 dogs and 0/3 cats), including the index case. Subsequently, MRSA was isolated from 3 of 12 animals on day 9; 3 of 9 animals on day 13; and none of 14, 5, and 6 animals on day 20, 27, and 78, respectively. Overall, MRSA was isolated from 6 of 26 (23%) animals during the outbreak period (4/22 dogs and 2/4 cats). The apparent incidence of MRSA acquisition in the ICU from days 1 through 13 was 20% (5/25 animals). No clinical signs of MRSA infections developed. All isolates were indistinguishable from one another.

TREATMENT AND OUTCOME

Infection-control measures including active surveillance of all animals in the ICU, barrier precautions, and hand hygiene were used to control the apparent outbreak.

CLINICAL RELEVANCE

Methicillin-resistant S aureus is an emerging problem in veterinary medicine. Intensive care units may be at particular risk for periodic outbreaks of colonization and disease. The outbreak of this report highlights the potential for clinically inapparent transmission of MRSA within a facility; infection-control measures that might facilitate MRSA eradication should be considered in ICU settings.

摘要

病例描述

从安大略兽医学院重症监护病房(ICU)的一只18个月大的去势雄性金毛猎犬的气管造口管中分离出耐甲氧西林金黄色葡萄球菌(MRSA)。这促使对ICU中其他动物的MRSA定植情况展开调查。

临床发现

在调查的第1天,从包括索引病例在内的10只动物中的2只(2/7只狗和0/3只猫)的鼻拭子中分离出MRSA。随后,在第9天从12只动物中的3只分离出MRSA;在第13天从9只动物中的3只分离出MRSA;在第20、27和78天,分别从14只、5只和6只动物中均未分离出MRSA。总体而言,在暴发期间从26只动物中的6只(23%)分离出MRSA(22只狗中的4只和4只猫中的2只)。从第1天到第13天,ICU中MRSA感染的表观发病率为20%(5/25只动物)。未出现MRSA感染的临床症状。所有分离株彼此无法区分。

治疗与结果

采取了包括对ICU中所有动物进行主动监测、屏障预防措施和手部卫生等感染控制措施来控制明显的暴发。

临床意义

耐甲氧西林金黄色葡萄球菌是兽医学中一个新出现的问题。重症监护病房可能特别容易出现定植和疾病的周期性暴发。本报告中的暴发突出了设施内MRSA临床不显性传播的可能性;在ICU环境中应考虑采取有助于根除MRSA的感染控制措施。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验