使用大麻在昔多芬的娱乐性使用中起作用吗？

Does marijuana use play a role in the recreational use of sildenafil?

作者信息

Eloi-Stiven Marie L, Channaveeraiah Naganna, Christos Paul J, Finkel Madelon, Reddy Rekha

机构信息

Department of Family Practice, Brooklyn Hospital Center, Brooklyn, NY; Department of Medicine, Weill Medical College of Cornell University, New York, NY USA.

出版信息

J Fam Pract. 2007 Nov;56(11):E1-4.

PMID:17976333

Abstract

PURPOSE

This study examined the ways by which patients obtain nonprescription sildenafil and the patient predictors associated with nonprescribed use.

METHODS

We conducted this descriptive study by distributing an anonymous questionnaire to 231 male sildenafil users (ages 18 to 80) between December 1, 2002 and April 30, 2003 at outpatient Family Medicine and Urology Clinics at The Brooklyn Hospital Center, Brooklyn, NY. Patients were divided into 2 groups: those with erectile dysfunction (as defined by their physician) and those without.

RESULTS

The prevalence of erectile dysfunction in our total study population of sildenafil users (n=231) was 40.3% (n=93); 59.7% (n=138) did not have erectile dysfunction. Of those without erectile dysfunction, 76% (n=105) admitted to cannabis use, compared with 7.5% (n=7) of the subjects with erectile dysfunction. Patients without erectile dysfunction and history of cannabis abuse reported obtaining sildenafil from friends and street vendors significantly more often than non-cannabis users with erectile dysfunction (54.3%, n=57 vs 9.3%, n=8; P<.0001).

CONCLUSIONS

Illicit use of cannabis is a strong predictor of recreational sildenafil use among patients without erectile dysfunction.

摘要

目的

本研究调查了患者获取非处方西地那非的方式以及与非处方使用相关的患者预测因素。

方法

2002年12月1日至2003年4月30日期间，我们在纽约布鲁克林布鲁克林医院中心的门诊家庭医学和泌尿外科诊所，向231名男性西地那非使用者（年龄18至80岁）发放了一份匿名问卷，以此进行这项描述性研究。患者被分为两组：有勃起功能障碍的患者（由其医生定义）和无勃起功能障碍的患者。

结果

在我们的西地那非使用者总研究人群（n = 231）中，勃起功能障碍的患病率为40.3%（n = 93）；59.7%（n = 138）没有勃起功能障碍。在那些没有勃起功能障碍的患者中，76%（n = 105）承认使用过大麻，而有勃起功能障碍的患者中这一比例为7.5%（n = 7）。没有勃起功能障碍且有大麻滥用史的患者报告从朋友和街头小贩处获取西地那非的频率明显高于有勃起功能障碍的非大麻使用者（54.3%，n = 57 vs 9.3%，n = 8；P <.0001）。