[乳腺典型髓样癌：33例回顾性研究]
[Typical medullary carcinoma of the breast: a retrospective study about 33 cases].
作者信息
Khomsi F, Ben Bachouche W, Bouzaiene H, Chargui R, Ben Hassouna J, Mtaalah M H, Dhiab T, Hechiche M, Benna F, Boussen H, Gamoudi A, Rahal K
机构信息
Service de Chirurgie Carcinologique, Institut Salah-Azaïz, Boulevard 9-Avril, 1006, Tunis, Tunisie.
出版信息
Gynecol Obstet Fertil. 2007 Nov;35(11):1117-22. doi: 10.1016/j.gyobfe.2007.08.022. Epub 2007 Oct 31.
OBJECTIVE
Typical medullary carcinoma of the breast is a rare histological form of breast carcinoma. It represents less than 5% of all breast cancer. It is known for its favourable prognosis. Considering the rarity of the series we could retrieve, we aimed at underlining the particularities of this pathology.
PATIENTS AND METHODS
Retrospective study about 33 cases of typical medullary carcinoma managed at the Salah-Azaïz Institute during a period of six years between 1994 and 1999.
RESULTS
The mean age was 47.5 years. The left breast was concerned in about 55% of cases. Mean tumoral size was 46mm. Sixty-one percent of our patients were treated by radical surgery. Seventy-three percent undergo radiotherapy, 57% chemotherapy and 42% hormonotherapy. The five-year free-disease survival was about 85%.
DISCUSSION AND CONCLUSION
Typical medullary carcinoma of the breast is a rare histological form of breast carcinoma. Its treatment is similar to the other breast cancers. Our results agree with the different published studies and confirm its favourable prognosis.
目的
典型乳腺髓样癌是一种罕见的乳腺癌组织学类型。它占所有乳腺癌的比例不到5%。其预后良好。鉴于我们能检索到的病例系列较少，我们旨在强调这种病理类型的特殊性。
患者与方法
对1994年至1999年期间在萨拉赫 - 阿扎伊兹研究所治疗的33例典型乳腺髓样癌病例进行回顾性研究。
结果
平均年龄为47.5岁。约55%的病例为左侧乳房发病。平均肿瘤大小为46毫米。61%的患者接受了根治性手术。73%的患者接受了放疗，57%接受了化疗，42%接受了激素治疗。五年无病生存率约为85%。
讨论与结论
典型乳腺髓样癌是一种罕见的乳腺癌组织学类型。其治疗方法与其他乳腺癌相似。我们的结果与已发表的不同研究一致，并证实了其良好的预后。
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