Raczyński Przemysław, Gburski Zygmunt
Institute of Physics, University of Silesia, Uniwersytecka 4, 40-007 Katowice, Poland.
Biomol Eng. 2007 Nov;24(5):568-71. doi: 10.1016/j.bioeng.2007.08.009. Epub 2007 Aug 7.
We have made the molecular dynamics (MD) simulations for the cluster of cholesterols localized near the protein farnesyltransferase (1FT2) at the physiological temperature T=309.75K. We have observed that the cholesterol molecules form a lodgment on the surface of protein. Several physical characteristics of the deposited cholesterol cluster have been calculated among those: the mean square displacement, diffusion coefficient, linear and angular velocity autocorrelation function and their Fourier transforms.
