Veysey E C, Wilkinson J D
Dermatology Department, Amersham Hospital, Amersham, Buckinghamshire, UK.
Clin Exp Dermatol. 2008 Jan;33(1):26-9. doi: 10.1111/j.1365-2230.2007.02546.x. Epub 2007 Nov 2.
We report a case of a 69-year-old woman with mycosis fungoides (MF), who presented with clinical and histological features of cutaneous lupus, and for 6 years was treated for this, until repeated biopsies and gene-rearrangement studies confirmed a diagnosis of MF. In addition, she developed thromboemboli and was found to have lupus anticoagulant antibodies. The possible biological relationship between antiphospholipid antibody syndrome and MF is considered. To our knowledge, this is the first reported case of MF masquerading as cutaneous lupus.
我们报告了一例69岁蕈样肉芽肿(MF)女性患者,其临床表现和组织学特征符合皮肤型红斑狼疮,为此接受了6年的治疗,直到重复活检和基因重排研究确诊为MF。此外,她发生了血栓栓塞,且发现存在狼疮抗凝抗体。本文考虑了抗磷脂抗体综合征与MF之间可能的生物学关系。据我们所知,这是首例伪装成皮肤型红斑狼疮的MF病例报告。