Huynh Vu, Lalezarzadeh Fariborz, Lawandy Shokry, Wong David T, Joe Victor C
Department of Emergency Medicine, Arrowhead Regional Medical Center, Colton, California 92324, USA.
Am Surg. 2007 Oct;73(10):1002-5.
Several studies report sensitivity and specificity of abdominal computed tomography scans (CT) for the evaluation of acute appendicitis as high as 98 per cent. Despite increased utilization of CT, the rate of negative appendectomy has remained constant at 10 to 20 per cent. The objective of this study was to assess the effectiveness of CT in the evaluation of acute and perforated appendicitis in an academic community-based setting. A retrospective review of 550 patient charts with International Classification of Diseases-9 (ICD-9) codes for acute and perforated appendicitis from January 2002 to October 2005 was performed. Sensitivity of CT was 87 per cent with a positive predictive value of 92 per cent. Specificity was 42 per cent with a negative predictive value of 29 per cent. Negative appendectomy rates were similar with or without CT (11% vs. 13%, respectively). Our data suggests that CT used liberally in everyday practice in a community-based setting to evaluate acute appendicitis may not have as strong of a diagnostic value as those used in protocol-driven research studies. Further prospective studies are needed to formulate criteria to better delineate the role of CT in the evaluation of acute appendicitis.
多项研究报告称,腹部计算机断层扫描(CT)用于评估急性阑尾炎时,其敏感度和特异度高达98%。尽管CT的使用有所增加,但阴性阑尾切除术的比例仍保持在10%至20%的恒定水平。本研究的目的是评估CT在学术性社区环境中对急性阑尾炎和穿孔性阑尾炎的评估效果。对2002年1月至2005年10月期间550例患有国际疾病分类第9版(ICD - 9)编码的急性阑尾炎和穿孔性阑尾炎患者的病历进行了回顾性分析。CT的敏感度为87%,阳性预测值为92%。特异度为42%,阴性预测值为29%。无论是否使用CT,阴性阑尾切除术的比例相似(分别为11%和13%)。我们的数据表明,在基于社区的日常实践中大量使用CT来评估急性阑尾炎,其诊断价值可能不如在方案驱动的研究中那么强。需要进一步进行前瞻性研究,以制定标准,更好地界定CT在评估急性阑尾炎中的作用。