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具有肾分化的脊髓畸胎瘤——一种罕见现象:两例病例报告

Spinal teratoma with renal differentiation--a rare phenomenon: report of two patients.

作者信息

Jain Deepali, Sharma Mehar Chand, Sarkar Chitra, Rishi Arvind, Suri Vaishali, Garg Ajay, Mahapatra Ashok Kumar

机构信息

Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.

出版信息

Clin Neurol Neurosurg. 2008 Mar;110(3):265-9. doi: 10.1016/j.clineuro.2007.09.016. Epub 2007 Nov 5.

Abstract

The occurrence of intradural spinal teratomas in association with spinal dysraphism is uncommon and even rarer is renal differentiation in a teratoma. We report two rare cases of patients with spinal dysraphism, split cord malformation and intraspinal teratomas with renal differentiation in a boy of 1 year and a girl of 3 years of age. Surgical excision of the mass, detethering of the cord and repair of the lipomyelomeningocele was done. Pathologic examination in both the cases revealed features of a mature teratoma with nephrogenic differentiation in the form of elements of mature renal tissue. To the best of our knowledge, spinal teratoma with renal component has not been described previously.

摘要

硬脊膜内脊髓畸胎瘤合并脊髓发育异常的情况并不常见,而畸胎瘤中出现肾分化则更为罕见。我们报告了两例罕见病例,一名1岁男孩和一名3岁女孩患有脊髓发育异常、脊髓纵裂畸形和具有肾分化的椎管内畸胎瘤。对肿块进行了手术切除,松解了脊髓并修复了脂肪瘤型脊髓脊膜膨出。两例病例的病理检查均显示为成熟畸胎瘤的特征,伴有以成熟肾组织成分形式存在的肾源性分化。据我们所知,此前尚未有关于具有肾成分的脊髓畸胎瘤的描述。

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