DeWan Andrew, Klein Robert J, Hoh Josephine
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA.
Methods Mol Biol. 2007;376:85-107. doi: 10.1007/978-1-59745-389-9_7.
In this chapter we lay out some background information about gene mapping for human complex traits. The chapter covers issues such as study design, high-throughput genotyping technologies, statistical analysis, and others. Many of the materials are based on and related to our recent experiences in case-control-association studies.
在本章中，我们阐述了一些关于人类复杂性状基因定位的背景信息。本章涵盖了研究设计、高通量基因分型技术、统计分析等问题。许多材料基于我们近期在病例对照关联研究中的经验并与之相关。
