一名感染人类免疫缺陷病毒的儿童出现与奈韦拉平相关的皮疹、嗜酸性粒细胞增多及全身症状。

Nevirapine-associated rash with eosinophilia and systemic symptoms in a child with human immunodeficiency virus infection.

作者信息

Santos Roberto P, Ramilo Octavio, Barton Theresa

机构信息

Department of Pediatrics, Division of Infectious Disease, University of Texas Southwestern Medical Center, Dallas, TX 75390-9063, USA.

出版信息

Pediatr Infect Dis J. 2007 Nov;26(11):1053-6. doi: 10.1097/INF.0b013e318125655d.

DOI:10.1097/INF.0b013e318125655d

PMID:17984815

Abstract

Drug rash with eosinophilia and systemic symptoms (DRESS Syndrome) associated with nevirapine treatment has not been previously reported in children. These findings can mimic other common illnesses, and treatment options are limited. We describe a 12-year-old girl infected with human immunodeficiency virus who developed hypersensitivity to nevirapine therapy. She was successfully treated with intravenous immune globulin.

摘要

奈韦拉平治疗相关的药物疹伴嗜酸性粒细胞增多和全身症状（DRESS综合征）此前尚未在儿童中报道。这些表现可类似其他常见疾病，且治疗选择有限。我们描述了一名感染人类免疫缺陷病毒的12岁女孩，她对奈韦拉平治疗产生了超敏反应。她通过静脉注射免疫球蛋白成功治愈。