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与奈韦拉平治疗相关的超敏反应综合征(DRESS)和脑膜脑炎。

Hypersensitivity syndrome (DRESS) and meningoencephalitis associated with nevirapine therapy.

作者信息

Lanzafame M, Rovere P, De Checchi G, Trevenzoli M, Turazzini M, Parrinello A

机构信息

Unità Operativa di Malattie Infettive, Ospedale Civile di Legnago, Verona, Italy.

出版信息

Scand J Infect Dis. 2001;33(6):475-6. doi: 10.1080/00365540152029990.

Abstract

The DRESS (drug rash with eosinophilia and systemic symptoms) syndrome is a serious condition that has been reported in association with various drugs, such as allopurinol, sulfonamides and aromatic anticonvulsants. Recently the condition has been described in HIV-infected patients taking antiretroviral agents. We report the first case, to our knowledge, of DRESS syndrome complicated by meningoencephalitis associated with nevirapine therapy.

摘要

药物超敏反应伴嗜酸性粒细胞增多和全身症状(DRESS)综合征是一种严重疾病,已报告与多种药物相关,如别嘌醇、磺胺类药物和芳香族抗惊厥药。最近,在服用抗逆转录病毒药物的HIV感染患者中也描述了这种情况。据我们所知,我们报告了首例与奈韦拉平治疗相关的并发脑膜脑炎的DRESS综合征病例。

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