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与奈韦拉平治疗相关的超敏反应综合征(DRESS)和脑膜脑炎。

Hypersensitivity syndrome (DRESS) and meningoencephalitis associated with nevirapine therapy.

作者信息

Lanzafame M, Rovere P, De Checchi G, Trevenzoli M, Turazzini M, Parrinello A

机构信息

Unità Operativa di Malattie Infettive, Ospedale Civile di Legnago, Verona, Italy.

出版信息

Scand J Infect Dis. 2001;33(6):475-6. doi: 10.1080/00365540152029990.

DOI:10.1080/00365540152029990
PMID:11450872
Abstract

The DRESS (drug rash with eosinophilia and systemic symptoms) syndrome is a serious condition that has been reported in association with various drugs, such as allopurinol, sulfonamides and aromatic anticonvulsants. Recently the condition has been described in HIV-infected patients taking antiretroviral agents. We report the first case, to our knowledge, of DRESS syndrome complicated by meningoencephalitis associated with nevirapine therapy.

摘要

药物超敏反应伴嗜酸性粒细胞增多和全身症状(DRESS)综合征是一种严重疾病,已报告与多种药物相关,如别嘌醇、磺胺类药物和芳香族抗惊厥药。最近,在服用抗逆转录病毒药物的HIV感染患者中也描述了这种情况。据我们所知,我们报告了首例与奈韦拉平治疗相关的并发脑膜脑炎的DRESS综合征病例。

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1
Hypersensitivity syndrome (DRESS) and meningoencephalitis associated with nevirapine therapy.与奈韦拉平治疗相关的超敏反应综合征(DRESS)和脑膜脑炎。
Scand J Infect Dis. 2001;33(6):475-6. doi: 10.1080/00365540152029990.
2
DRESS (drug rash with eosinophilia and systemic symptoms) syndrome associated with nevirapine therapy.与奈韦拉平治疗相关的药物疹伴嗜酸性粒细胞增多和系统症状(DRESS)综合征。
Clin Infect Dis. 1998 Nov;27(5):1321-2.
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Nevirapine-induced rash with eosinophilia and systemic symptoms (DRESS).奈韦拉平引起的皮疹伴嗜酸性粒细胞增多和全身症状(DRESS)。
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Case reports: treatment of nevirapine-associated dress syndrome with intravenous immune globulin (IVIG).病例报告:静脉注射免疫球蛋白(IVIG)治疗奈韦拉平相关的药物超敏反应综合征。
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DRESS syndrome associated with nevirapine therapy.
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Drug rash with eosinophilia and systemic symptoms (DRESS syndrome).药物疹伴嗜酸性粒细胞增多和全身症状(DRESS综合征)。
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引用本文的文献

1
Drug reaction with eosinophilia and systemic symptoms related to antiretroviral treatment in human immunodeficiency virus patients.人类免疫缺陷病毒患者中与抗逆转录病毒治疗相关的伴有嗜酸性粒细胞增多和全身症状的药物反应。
Indian J Sex Transm Dis AIDS. 2017 Jul-Dec;38(2):163-170. doi: 10.4103/ijstd.IJSTD_70_17.
2
Reversible Vegetative State in a Child Due to Drug Reaction with Eosinophilia and Systemic Symptoms.药物反应伴嗜酸性粒细胞增多和全身症状导致儿童可逆性植物状态。
Indian J Pediatr. 2017 Mar;84(3):249-250. doi: 10.1007/s12098-016-2265-1. Epub 2016 Dec 7.
3
Extensive pulmonary involvement with raltegravir-induced DRESS syndrome in a postpartum woman with HIV.
一名产后感染艾滋病毒的妇女出现广泛肺部受累的拉替拉韦诱导的药物反应伴嗜酸性粒细胞增多和系统症状综合征。
BMJ Case Rep. 2014 May 5;2014:bcr2013201545. doi: 10.1136/bcr-2013-201545.
4
DRESS Syndrome due to Nevirapine Treated with Methylprednisolone.奈韦拉平所致药物超敏反应伴嗜酸性粒细胞增多和系统症状(DRESS)综合征用甲泼尼龙治疗
Case Rep Med. 2013;2013:269501. doi: 10.1155/2013/269501. Epub 2013 Aug 1.
5
Persistent high nevirapine blood level with DRESS syndrome 12 days after interruption of antiretroviral therapy.抗逆转录病毒治疗中断12天后,奈韦拉平血药浓度持续升高并出现药物超敏反应综合征。
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.07.2008.0475. Epub 2009 Mar 17.
6
Safety and efficacy of a generic fixed-dose combination of stavudine, lamivudine and nevirapine antiretroviral therapy between HIV-infected patients with baseline CD4 <50 versus CD4 > or = 50 cells/mm3.基线CD4<50个细胞/立方毫米与CD4≥50个细胞/立方毫米的HIV感染患者之间,司他夫定、拉米夫定和奈韦拉平抗逆转录病毒疗法通用固定剂量组合的安全性和疗效。
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Curr Infect Dis Rep. 2003 Oct;5(5):429-438. doi: 10.1007/s11908-003-0023-9.