真核生物转座元件的统一分类系统。

A unified classification system for eukaryotic transposable elements.

作者信息

Wicker Thomas, Sabot François, Hua-Van Aurélie, Bennetzen Jeffrey L, Capy Pierre, Chalhoub Boulos, Flavell Andrew, Leroy Philippe, Morgante Michele, Panaud Olivier, Paux Etienne, SanMiguel Phillip, Schulman Alan H

机构信息

Institute of Plant Biology, University Zurich, Zollikerstrasse 107, CH-8008 Zurich, Switzerland.

出版信息

Nat Rev Genet. 2007 Dec;8(12):973-82. doi: 10.1038/nrg2165.

DOI:10.1038/nrg2165

PMID:17984973

Abstract

Our knowledge of the structure and composition of genomes is rapidly progressing in pace with their sequencing. The emerging data show that a significant portion of eukaryotic genomes is composed of transposable elements (TEs). Given the abundance and diversity of TEs and the speed at which large quantities of sequence data are emerging, identification and annotation of TEs presents a significant challenge. Here we propose the first unified hierarchical classification system, designed on the basis of the transposition mechanism, sequence similarities and structural relationships, that can be easily applied by non-experts. The system and nomenclature is kept up to date at the WikiPoson web site.

摘要

随着基因组测序技术的发展，我们对基因组结构和组成的了解正在迅速进步。新出现的数据表明，真核生物基因组的很大一部分是由转座元件（TEs）组成的。鉴于TEs的丰富性和多样性以及大量序列数据出现的速度，TEs的识别和注释面临着重大挑战。在此，我们提出了第一个统一的层次分类系统，该系统基于转座机制、序列相似性和结构关系设计，非专业人员也可轻松应用。该系统和命名法在WikiPoson网站上保持更新。