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新生儿手术的成本效益:起初受到怀疑,如今越来越被接受。

Cost-effectiveness of neonatal surgery: first greeted with scepticism, now increasingly accepted.

作者信息

Poley Marten J, Brouwer Werner B F, Busschbach Jan J V, Hazebroek Frans W J, Tibboel Dick, Rutten Frans F H, Molenaar Jan C

机构信息

Department of Paediatric Surgery, Sophia Children's Hospital, Erasmus MC, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands.

出版信息

Pediatr Surg Int. 2008 Feb;24(2):119-27. doi: 10.1007/s00383-007-2045-0. Epub 2007 Nov 6.

DOI:10.1007/s00383-007-2045-0
PMID:17985140
Abstract

Mortality rates in neonatal surgery have dropped markedly, illustrating the enormous progress made. Yet, new questions have arisen. To mention one, health care budgets have tightened. It follows that the effects of medical interventions should be weighted against their costs. As evidence was particularly sparse, we set out to analyse cost-effectiveness of neonatal surgery. The purpose of this article is to summarise our findings and to review recent studies. Moreover, this article explains the relevance of cost-effectiveness analysis and explores how cost-effectiveness interacts with other determinants of health care priority setting. Our research revealed that treatments for two common diagnostic categories in neonatal surgery (congenital anorectal malformations and congenital diaphragmatic hernia) produce good cost-effectiveness. Other groups also published cost-effectiveness studies in the field of neonatal surgery, although their number is still small. Contemporaneously, the economic aspects of health care have captured the interest of policy makers. Importantly, this is not to say that there are no other factors playing a role in priority setting, foremost among which are ethical questions and arguments of equity. This article concludes that, according to present evidence, neonatal surgery yields good value for money and contributes to equity in health.

摘要

新生儿外科的死亡率已显著下降,这表明取得了巨大进展。然而,新的问题也随之出现。仅举一例,医疗保健预算已收紧。因此,医疗干预的效果应与其成本相权衡。由于证据特别稀少,我们着手分析新生儿外科的成本效益。本文的目的是总结我们的研究结果并回顾近期的研究。此外,本文解释了成本效益分析的相关性,并探讨了成本效益如何与医疗保健优先事项设定的其他决定因素相互作用。我们的研究表明,新生儿外科中两种常见诊断类型(先天性肛门直肠畸形和先天性膈疝)的治疗具有良好的成本效益。其他团队也发表了新生儿外科领域的成本效益研究,尽管数量仍然很少。与此同时,医疗保健的经济方面已引起政策制定者的关注。重要的是,这并不是说在优先事项设定中没有其他因素发挥作用,其中最主要的是伦理问题和公平性论点。本文得出结论,根据目前的证据,新生儿外科性价比高,并有助于实现健康公平。

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Cost-effectiveness of neonatal surgery for congenital anomalies in low-income and middle-income countries: a systematic review protocol.低收入和中等收入国家先天性异常新生儿手术的成本效益:一项系统评价方案
BMJ Paediatr Open. 2020 Aug 30;4(1):e000755. doi: 10.1136/bmjpo-2020-000755. eCollection 2020.
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Emergency repair of inguinal hernia in the premature infant is associated with high direct medical costs.

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Health-related quality of life in adults after repair of congenital diaphragmatic defects--a questionnaire study.先天性膈缺陷修复术后成人的健康相关生活质量——一项问卷调查研究
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Critical factors affecting quality of life of adult patients with anorectal malformations or Hirschsprung's disease.影响肛门直肠畸形或先天性巨结肠成年患者生活质量的关键因素。
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Does NICE have a cost-effectiveness threshold and what other factors influence its decisions? A binary choice analysis.国家卫生与临床优化研究所(NICE)是否有成本效益阈值,以及还有哪些其他因素影响其决策?一项二元选择分析。
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Cost effectiveness analysis of neonatal extracorporeal membrane oxygenation based on four year results from the UK Collaborative ECMO Trial.基于英国体外膜肺氧合协作试验四年结果的新生儿体外膜肺氧合成本效益分析。
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