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髋臼窝多处钻孔可在髋臼旋转截骨术治疗髋关节发育不良后诱导早期关节重塑。

Multiple drillings of the acetabular fossa induce early joint remodeling after rotational acetabular osteotomy for hip dysplasia.

作者信息

Yamasaki Takuma, Yasunaga Yuji, Terayama Hiroshi, Hamaki Takanari, Deie Masataka, Ochi Mitsuo

机构信息

Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima, Japan.

出版信息

Arch Orthop Trauma Surg. 2008 Sep;128(9):909-13. doi: 10.1007/s00402-007-0493-6. Epub 2007 Nov 6.

Abstract

INTRODUCTION

We previously observed medial and/or lateral expansion of the subchondral bone in the acetabulum 3 years postoperatively in two out of three cases in which rotational acetabular osteotomy (RAO) was performed. Then we performed multiple drillings at the acetabular fossa in order to induce expansion of the medial subchondral bone in the acetabulum. The purpose of this study is to evaluate the effect of multiple drillings on early joint remodeling after RAO.

PATIENTS AND METHODS

Twenty-one women (21 joints) who had undergone RAO with multiple drillings at acetabular fossa (group D) were included. As a control group, 12 women (14 joints) without drillings in RAO procedure were observed (group C). The center-edge angle (CE angle), acetabular roof obliquity (AC angle), head lateralization index (HLI), and the angle between medial and lateral edge of acetabular roof (LOM angle) were measured on the radiographs preoperatively, at 1 month, 2 years postoperatively, and at the last follow-up.

RESULTS

As regards the mean CE angle, AC angle, and HLI, there was no significant difference between the two groups. The mean LOM angle at 2 years and the last follow-up demonstrated significant difference between the two groups.

INTERPRETATION

Biomechanical and anatomical changes after RAO cause increasing stress to the medial side of the acetabulum. Moreover, bone marrow-stimulating procedure at acetabular fossa might be beneficial to develop early joint remodeling affected by bone marrow derived cells such as mesenchymal stem cells.

摘要

引言

我们之前观察到,在接受髋臼旋转截骨术(RAO)的三例患者中,有两例在术后3年出现髋臼软骨下骨的内侧和/或外侧扩张。随后,我们在髋臼窝进行了多次钻孔,以诱导髋臼内侧软骨下骨扩张。本研究的目的是评估多次钻孔对RAO术后早期关节重塑的影响。

患者与方法

纳入21例接受RAO并在髋臼窝进行多次钻孔的女性患者(21个关节)(D组)。作为对照组,观察12例在RAO手术中未进行钻孔的女性患者(14个关节)(C组)。在术前、术后1个月、术后2年及末次随访时,通过X线片测量中心边缘角(CE角)、髋臼顶倾斜角(AC角)、股骨头侧化指数(HLI)以及髋臼顶内侧和外侧边缘之间的夹角(LOM角)。

结果

两组的平均CE角、AC角和HLI无显著差异。两组在术后2年及末次随访时的平均LOM角存在显著差异。

解读

RAO术后的生物力学和解剖学变化导致髋臼内侧应力增加。此外,髋臼窝的骨髓刺激程序可能有利于受间充质干细胞等骨髓来源细胞影响的早期关节重塑。

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