Iakobson G S, Gizatulin Z Ia, Shorin Iu P, Subbotin V M
Farmakol Toksikol. 1975 May-Jun;38(3):349-52.
Introduction of CCI4 in doses of 0.1 and 0.2 ml/100 g to albino rats reduced the steroid production generated by adrenal sections. In 24 and 48 hours after poisoning with a small dose of CCI4 (0.1 ml/100 g) there could be seen an increased concentration of 11-oxycorticosteroids in the plasma. Morphological signs of a damage suffered by the gland were observed only in poisoning with a large dose of CCI4 (0.2 ml/100 g).
给白化大鼠注射剂量为0.1和0.2毫升/100克的四氯化碳,会降低肾上腺切片产生的类固醇。在用小剂量四氯化碳(0.1毫升/100克)中毒后的24小时和48小时,可以看到血浆中11 - 氧皮质类固醇的浓度增加。仅在用大剂量四氯化碳(0.2毫升/100克)中毒时才观察到肾上腺受损的形态学迹象。