准分子激光原位角膜磨镶术（LASIK）6年后板层床发生腐败希瓦氏菌角膜炎。
Shewanella putrefaciens keratitis in the lamellar bed 6 years after LASIK.
作者信息
Park Hee-Jung S, Tuli Sonal S, Downer Donald M, Gohari A Reza, Shah Milan
机构信息
Department of Ophthalmology, University of Florida, Gainesville, Fla, USA.
出版信息
J Refract Surg. 2007 Oct;23(8):830-2. doi: 10.3928/1081-597X-20071001-15.
PURPOSE
To present a case of infectious keratitis occurring 6 years after LASIK due to the rare human pathogen Shewanella putrefaciens.
METHODS
A 58-year-old man presented with redness and pain in the right eye 6 years following LASIK retreatment. Examination revealed a corneal infiltrate at the flap interface. Corneal scraping of stroma beneath the flap was submitted for histopathologic and microbiologic evaluation.
RESULTS
An infiltrate located at the LASIK flap interface originated from an epithelial defect at the flap-corneal junction. Corneal stroma cultures demonstrated Shewanella putrefaciens. The infection resolved with antibiotic treatment.
CONCLUSIONS
LASIK-related complications, such as infections, can occur many years following the procedure. The potential space created under the LASIK flap may predispose patients to infection by opportunistic organisms.
目的
报告一例准分子激光原位角膜磨镶术（LASIK）6年后因罕见的人类病原体腐败希瓦氏菌引起感染性角膜炎的病例。
方法
一名58岁男性在LASIK再次治疗6年后出现右眼红肿和疼痛。检查发现瓣界面处有角膜浸润。对瓣下基质进行角膜刮片，送去做组织病理学和微生物学评估。
结果
位于LASIK瓣界面处的浸润源自瓣 - 角膜交界处的上皮缺损。角膜基质培养显示有腐败希瓦氏菌。经抗生素治疗感染得到解决。
结论
LASIK相关并发症，如感染，可在手术多年后发生。LASIK瓣下形成的潜在间隙可能使患者易受机会性生物体感染。
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