泪囊原发性非霍奇金淋巴瘤
Primary non Hodgkin's lymphoma of the lacrimal sac.
作者信息
Venkitaraman Ramachandran, George Mathew K
机构信息
Division of Medical Oncology, Royal Darwin Hospital, Casuarina, Australia.
出版信息
World J Surg Oncol. 2007 Nov 6;5:127. doi: 10.1186/1477-7819-5-127.
BACKGROUND
Primary Non Hodgkin's Lymphoma (NHL) of the lacrimal sac is rare.
METHODS
The clinical features of a 78 year old female who presented with epiphora and swelling of the left lacrimal sac are described.
RESULTS
Computerised tomography showed a mass involving the left lacrimal sac. Histopathological examination revealed a diffuse large B cell NHL. Immunohistological examination demonstrated B cell origin. Chemotherapy could not be administered due to co morbid conditions. The patient was treated with radiotherapy to a dose of 45 Gy in 25 fractions. Patient is disease free and on follow up after 36 months.
CONCLUSION
Primary radiotherapy is a treatment option with curative potential for localized NHL of the lacrimal sac and may be considered in patients who cannot tolerate appropriate chemotherapy.
背景
泪囊原发性非霍奇金淋巴瘤（NHL）较为罕见。
方法
描述了一名78岁女性患者的临床特征，该患者表现为溢泪和左泪囊肿胀。
结果
计算机断层扫描显示左泪囊有肿物。组织病理学检查显示为弥漫性大B细胞NHL。免疫组织学检查证实为B细胞起源。由于并存疾病无法进行化疗。患者接受了放疗，剂量为45 Gy，分25次给予。患者疾病无进展，36个月后仍在随访中。
结论
对于泪囊局限性NHL，原发性放疗是一种具有治愈潜力的治疗选择，对于无法耐受适当化疗的患者可考虑采用。
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