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[关于使用全氟碳乳剂对离体心脏进行常温灌注可能性的评估]

[The evaluation of the possibility of using a perfluorocarbon emulsion for the normothermic perfusion of the isolated heart].

作者信息

Vorob'ev S I, Vasil'ev A E, Islamov B I, Kravchenko V V

出版信息

Patol Fiziol Eksp Ter. 1991 Jul-Aug(4):34-6.

PMID:1798650
Abstract

Complex study of isolated heart preparations according to some electromechanical, biochemical, gas transport, and morphofunctional criteria showed that a perfusion medium based on an emulsion of perfluorocarbons ensures an essentially better survival of a heart perfused in a recirculation regimen than with the traditionally used Krebs-Henseleite solution. The analysis shows that the use of perfluorocarbon emulsions as a perfusion medium for prolonged storage of isolated organs is promising.

摘要

根据一些机电、生化、气体运输和形态功能标准对离体心脏制剂进行的综合研究表明,基于全氟化碳乳液的灌注介质能确保在循环灌注方案下灌注的心脏比使用传统的克雷布斯 - 亨泽莱特溶液具有更好的存活效果。分析表明,使用全氟化碳乳液作为离体器官长期保存的灌注介质具有广阔前景。

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