Vorob'ev S I, Ladilov Iu V, Obraztsov V V, Ivanitskiĭ G R
Biull Eksp Biol Med. 1990 Jul;110(7):19-21.
The study was conducted to determine if myocardium can be protected against ischemic and reperfusion damage by means of the preliminarily injected perfluorocarbon emulsion. Injection of the emulsion into rabbit 1, 12, 24 h prior to ischemia was found to decrease the extent of ischemic and reperfusion damage to myocardium. The cardiotropic effect of the injected emulsion is shown to be dose- and time dependent.
进行该研究以确定预先注射全氟碳乳剂是否可以保护心肌免受缺血和再灌注损伤。发现在缺血前1小时、12小时、24小时给兔子注射乳剂可减少心肌缺血和再灌注损伤的程度。注射乳剂的强心作用表现为剂量和时间依赖性。
