Jemiolo B, Xie T M, Novotny M
Chemistry Department, Indiana University, Bloomington 47405.
Physiol Behav. 1991 Dec;50(6):1119-22. doi: 10.1016/0031-9384(91)90570-e.
Two sesquiterpenic compounds, E,E,-alpha-farnesene and E-beta-farnesene, which were previously found as major constituents of the male mouse preputial glands, were tested for their attractiveness to female mice. Sexually naive and sexually experienced females were given the opportunity to choose between natural stimuli and synthetic analogs of preputial chemosignals. Naive females preferred investigating the odors of intact males' urine and synthetic farnesenes when spiked in high concentration in bladder urine or water over control stimulus (water or bladder urine alone). Investigatory preference was not observed when synthetic farnesenes were presented to naive females in low concentration, i.e., only twice the natural content in the dominant male urine. However, sexually experienced females were clearly able to recognize and prefer samples with synthetic farnesenes, even in low concentration. We suggest that those sesquiterpenic compounds may play a wide-ranging role in the female recognition of sexually mature and socially dominant males.
两种倍半萜化合物，即E,E-α-法尼烯和E-β-法尼烯，它们先前被发现是雄性小鼠包皮腺的主要成分，此次对其对雌性小鼠的吸引力进行了测试。性幼稚和有性经验的雌性小鼠有机会在自然刺激和包皮化学信号的合成类似物之间进行选择。性幼稚的雌性小鼠在膀胱尿液或水中高浓度添加完整雄性小鼠尿液和合成法尼烯的气味时，相较于对照刺激物（单独的水或膀胱尿液），更倾向于探究这些气味。当以低浓度向性幼稚的雌性小鼠呈现合成法尼烯时，即仅为优势雄性尿液中天然含量的两倍时，未观察到探究偏好。然而，有性经验的雌性小鼠即使在低浓度下也能清楚地识别并偏好含有合成法尼烯的样本。我们认为，这些倍半萜化合物可能在雌性识别性成熟和社会优势雄性方面发挥广泛作用。
