Urine marking in male mice: responses to natural and synthetic chemosignals.

The effects of natural chemosignals and their synthetic terpenic analogs on urinary marking in mice were investigated. The number and size of marking spots, and percentage of response and avoidance/counter-marking behavior, were measured for dominant and subordinate males. The males' marking behavior was found to differ significantly based on the type of stimulus sample used. Marking behavior in response to female urine was significantly altered by addition of synthetic analogs (farnesene isomers) to it. Both dominant and subordinate males avoided marking the section of the test area soiled with stimulus samples containing either natural or synthetic farnesenes. Differential responses of the dominant and subordinate male mice were observed.