Yilmaz M, Tiryaki O, Namiduru M, Okan V, Oguz A, Buyukhatipoglu H, Karaoglan I, Yilmaz B
Department of Haematology, Gaziantep University School of Medicine, Gaziantep, Turkey.
Int J Lab Hematol. 2007 Dec;29(6):442-5. doi: 10.1111/j.1365-2257.2006.00880.x.
Brucellosis continues to be an important cause of fever in underdeveloped countries and in rural areas of developed world. It is a multisystemic disease, associated with wide variety of symptoms. A wide variety of symptoms, including haematological abnormalities, such as anaemia, thrombocytopenia, pancytopenia, dissemine intravascular coagulation and leucopoenia could be seen, all of which are more common than usually thought. In this short study, we present a relatively uncommon haematological manifestation that of isolated thrombocytopenia mimicking idiopathic thrombocytopenic purpura, which we observed in seven of 114 patients who were diagnosed with brucellosis in our hospital over a 2-year period. Having given brucellosis treatment with rifampicin and doxycycline, complete remission was achieved and thrombocyte count returned to normal in all cases.
布鲁氏菌病仍是欠发达国家以及发达国家农村地区发热的重要病因。它是一种多系统疾病,伴有多种症状。可见多种症状,包括血液学异常,如贫血、血小板减少、全血细胞减少、弥散性血管内凝血和白细胞减少,所有这些都比通常认为的更为常见。在这项简短的研究中,我们呈现了一种相对罕见的血液学表现,即孤立性血小板减少,酷似特发性血小板减少性紫癜,这是我们在两年期间于我院确诊的114例布鲁氏菌病患者中的7例身上观察到的。给予利福平和强力霉素治疗布鲁氏菌病后,所有病例均实现完全缓解,血小板计数恢复正常。