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儿童和青年成人创伤性脑损伤:来自芬兰北部的一项出生队列研究。

Traumatic brain injuries in children and young adults: a birth cohort study from northern Finland.

作者信息

Winqvist Satu, Lehtilahti Maria, Jokelainen Jari, Luukinen Heikki, Hillbom Matti

机构信息

Department of Neurology, University of Oulu and Oulu University Hospital, Oulun Yliopisto, Finland.

出版信息

Neuroepidemiology. 2007;29(1-2):136-42. doi: 10.1159/000110741. Epub 2007 Nov 7.

Abstract

AIMS

Incidence and mortality rates of traumatic brain injury (TBI) were investigated by using the Northern Finland Birth Cohort. This cohort provides a valuable source of data from the population born in 1966 (n = 12,058) in the 2 northernmost provinces of Finland.

METHODS

The cohort was followed for 34 years, and data were gathered from the Finnish Hospital Discharge Register and the Registry for Causes of Death by Statistics Finland.

RESULTS

The annual incidence of and mortality from TBI were 118 and 14/100,000, respectively. Case fatality was 12%. An estimated prevalence of TBI at the age of 34 years was 269/100,000. Peak occurrences were observed at the age of 6-7 years in both genders and at the age of 18-23 years in men. The proportion of TBI mortality out of total mortality was 12%. Young men aged 16-34 years had 10-fold proportionate mortality from TBI compared to boys aged <or=15 years. Alcohol drinking was associated with a particularly prominent number of intentional injuries in young men.

CONCLUSION

Incidence and mortality rates of TBI vary according to age and gender. Peaks occur in children at the age of school entry and in men at the age of 18-23 years. Children have mild injuries, whereas the injuries of young men are frequently intentional and fatal and associated with alcohol drinking.

摘要

目的

利用芬兰北部出生队列研究创伤性脑损伤(TBI)的发病率和死亡率。该队列提供了来自芬兰最北部两个省份1966年出生人群(n = 12,058)的宝贵数据来源。

方法

对该队列进行了34年的随访,并从芬兰医院出院登记册和芬兰统计局死因登记处收集数据。

结果

TBI的年发病率和死亡率分别为118/100,000和14/100,000。病死率为12%。34岁时TBI的估计患病率为269/100,000。男女在6 - 7岁时均出现发病高峰,男性在18 - 23岁时出现发病高峰。TBI死亡占总死亡的比例为12%。16 - 34岁的年轻男性因TBI导致的比例死亡率是≤15岁男孩的10倍。饮酒与年轻男性中特别多的故意伤害有关。

结论

TBI的发病率和死亡率因年龄和性别而异。发病高峰出现在儿童入学年龄以及男性18 - 23岁时。儿童的损伤较轻,而年轻男性的损伤往往是故意造成的,且致命,并与饮酒有关。

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