Wu Xing, Hu Jin, Zhuo Liangfu, Fu Chaowei, Hui Guozhen, Wang Yehan, Yang Weizhong, Teng Liangzhu, Lu Sitin, Xu Gengsheng
Neurosurgery Department, Huashan Hospital, Fudan University, Shanghai, China.
J Trauma. 2008 May;64(5):1313-9. doi: 10.1097/TA.0b013e318165c803.
Traumatic brain injury (TBI) is the leading cause of death for traumatic injury, which is the fifth highest killer in China and the highest killer in adults under 40 years of age. But, there is a lack of epidemiologic data of TBI in China during the past decade. This study aimed to investigate the epidemiologic data of TBI in eastern China, based on a prospective multicenter trial.
Data were collected from the 77 hospitals by standardized structured questionnaires in this region during the 1-year period (2004).
A total of 14,948 of cases of traumatic brain injury were identified from 77 hospitals in eastern China. There were 11,446 men (76.6%) and 3,502 women (25.4%). Male adolescents and young adults were affected more often by brain injury. Traffic accidents (60.9%), knock on head (13.4%), and falls (13.1%) were the leading causes of patients with TBI. Approximately one-thirds of the traffic-related TBI were motorcyclists, 31% were pedestrians, and 21.9% were cyclists, whereas motor vehicle occupants only counted for 14% of the cases. The distribution of head injury severity, on the basis of Glasgow Coma Scale scores, was mild in 62%, moderate in 18.1%, and severe in 20% for all cases. The traffic accidents caused the most of severe injuries, which accounted for about 70.4%. Based on Glasgow Outcome Scale assessment, 10.8% of the patients died, 2.6% were in vegetation status, 2.2% had severe disability, 7.2% had moderate disability, and 77.3% had good recovery. And, the outcome depended on age, injury mechanism and initial Glasgow Coma Scale score.
The prospective cohort study shows an alteration of TBI during the past decade in eastern China. It is essential to establish a standardized surveillance system of TBI incidence, risk factors, causes, and outcomes for development of new, more effective, targeted strategies to prevent TBI.
创伤性脑损伤（TBI）是创伤性损伤的主要死因，在中国是第五大致死原因，在40岁以下成年人中是首要死因。但是，过去十年中国缺乏TBI的流行病学数据。本研究旨在基于一项前瞻性多中心试验调查中国东部地区TBI的流行病学数据。
在2004年的1年期间，通过标准化结构化问卷从该地区的77家医院收集数据。
在中国东部地区的77家医院共识别出14948例创伤性脑损伤病例。其中男性11446例（76.6%），女性3502例（25.4%）。男性青少年和年轻人更容易受到脑损伤影响。交通事故（60.9%）、头部撞击（13.4%）和跌倒（13.1%）是TBI患者的主要病因。约三分之一与交通相关的TBI患者是骑摩托车者，31%是行人，21.9%是骑自行车者，而机动车乘客仅占病例的14%。根据格拉斯哥昏迷量表评分，所有病例中头部损伤严重程度分布为轻度占62%，中度占18.1%，重度占20%。交通事故导致的重伤最多，约占70.4%。根据格拉斯哥预后量表评估，10.8%的患者死亡，2.6%处于植物状态，2.2%有严重残疾，7.2%有中度残疾，77.3%恢复良好。而且，预后取决于年龄、损伤机制和初始格拉斯哥昏迷量表评分。
前瞻性队列研究显示中国东部地区过去十年TBI情况有所变化。建立TBI发病率、危险因素、病因和预后的标准化监测系统对于制定新的、更有效、有针对性的TBI预防策略至关重要。
