Nygren Jonas, Thorell Anders, Ljungqvist Olle
Centre of GastroIntestinal Disease, Ersta Hospital, and Karolinska Institutet and CLINTEC, Karolinska University Hospital Huddinge, Stockholm, Sweden.
Curr Opin Anaesthesiol. 2007 Dec;20(6):540-4. doi: 10.1097/ACO.0b013e3282f15493.
As a result of advances in anaesthesia and surgery, an increasing number of surgical procedures are currently possible in the ambulatory setting. Nausea/vomiting and sedation/drowsiness are often associated with delayed discharge and readmission. These symptoms are also related to pharmacological treatment as well as dehydration and fasting. The evidence that preoperative fasting and dehydration not only reduces preoperative well being, but may also affect postoperative recovery is currently being reviewed.
In association with minor surgical procedures, rehydration with approximately 1 l fluid, and in cases with a moderate degree of surgery, such as laparoscopic surgery, 1-3 l fluid, given perioperatively will improve postoperative well being and recovery. Administration of a carbohydrate-rich beverage not only provides fluid but also counteracts the negative effects of preoperative fasting, which in turn reduces preoperative hunger and improves well being. Postoperatively, this treatment reduces insulin resistance, which may be relevant in surgery with significant postoperative stress response. Two studies on laparoscopic cholecystectomy demonstrate different results regarding effects on postoperative outcome and nausea/vomiting and further evaluation is required.
When preoperative dehydration is corrected, postoperative well being and clinical outcome improves. Avoiding preoperative fasting by administration of carbohydrate-rich beverages improves preoperative well being while effects on postoperative recovery in patients undergoing ambulatory surgery need to be further evaluated.
由于麻醉和外科手术的进展,目前越来越多的外科手术可以在门诊环境中进行。恶心/呕吐以及镇静/嗜睡常常与延迟出院和再次入院相关。这些症状也与药物治疗以及脱水和禁食有关。目前正在对术前禁食和脱水不仅会降低术前舒适度,还可能影响术后恢复的证据进行审查。
对于小型外科手术,围手术期给予约1升液体进行补液,对于中等程度手术如腹腔镜手术,则给予1 - 3升液体,这将改善术后舒适度和恢复情况。给予富含碳水化合物的饮料不仅能补充液体,还能抵消术前禁食的负面影响,进而减轻术前饥饿感并改善舒适度。术后,这种治疗可降低胰岛素抵抗,这在术后有显著应激反应的手术中可能具有重要意义。两项关于腹腔镜胆囊切除术的研究在对术后结局以及恶心/呕吐的影响方面显示出不同结果,需要进一步评估。
纠正术前脱水后,术后舒适度和临床结局会得到改善。通过给予富含碳水化合物的饮料避免术前禁食可改善术前舒适度,而其对门诊手术患者术后恢复的影响有待进一步评估。