Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia (USM), 16150, Kubang Kerian, Kelantan, Malaysia.
Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.
Sci Rep. 2023 Nov 16;13(1):20078. doi: 10.1038/s41598-023-47357-5.
Prolonged fasting prior to oesophagogastroduodenoscopy (OGDS) could be noxious to patients' well-being. Strict fasting protocol has been used prior to OGDS with the concern of reduced visibility or suboptimal endoscopic assessment. Maltodextrin beverages were also commonly used as the pre-operative carbohydrate loading in enhanced recovery after surgery (ERAS) protocol. Our study aimed to look for the effects of maltodextrin beverage 2 h before OGDS on gastric residual volume and patient's well-being scores. This was a single-blinded, stratified randomised controlled trial, comparing control group (A, received 400 ml of plain water) and carbohydrate loading group (B, received 400 ml of Carborie). The primary objectives were to measure the gastric residual volume (GRV) and patient's well-being scores using visual analogue scale (VAS) scores for hunger, thirst, anxiety, tiredness and general discomfort. Of 80 randomised patients, 78 completed the study (38 received plain water and 40 Carborie). The median (IQR) GRV was not significantly different between group A and B (5.0 ml (20) vs 4.0 ml (19), p = 0.777). Both groups showed significant reduction in VAS scores in all five parameters (p ≤ 0.001). There were no complications attributed to endoscopy in either group. Pre-endoscopy maltodextrin beverage is as safe as clear water with improved patient's well-being in both groups.Clinical Trial Registration: NCT05106933.
在进行食管胃十二指肠镜检查(OGDS)之前长时间禁食可能对患者的健康有害。在进行 OGDS 之前,人们一直采用严格的禁食方案,因为担心会降低可见度或使内镜评估效果不佳。麦芽糊精饮料也常用于手术后加速康复(ERAS)方案中的术前碳水化合物负荷。我们的研究旨在探讨 OGDS 前 2 小时饮用麦芽糊精饮料对胃残留量和患者舒适度评分的影响。这是一项单盲、分层随机对照试验,比较了对照组(A,饮用 400ml 白开水)和碳水化合物负荷组(B,饮用 400ml Carborie)。主要目的是使用视觉模拟量表(VAS)评分测量胃残留量(GRV)和患者的舒适度评分,用于评估饥饿、口渴、焦虑、疲劳和总体不适。在 80 名随机患者中,有 78 名完成了研究(38 名接受白开水,40 名接受 Carborie)。A 组和 B 组的中位(IQR)GRV 无显著差异(5.0ml(20)比 4.0ml(19),p=0.777)。两组在所有五个参数的 VAS 评分均显著降低(p≤0.001)。两组均无与内镜相关的并发症。在两组中,内镜检查前饮用麦芽糊精饮料与饮用白开水一样安全,并可改善患者的舒适度。临床试验注册:NCT05106933。