Superparamagnetic gamma-Fe(2)O(3) nanoparticles with tailored functionality for protein separation.
作者信息
Shukoor Mohammed Ibrahim, Natalio Filipe, Tahir Muhammad Nawaz, Ksenofontov Vadim, Therese Helen Annal, Theato Patrick, Schröder Heinz C, Müller Werner E G, Tremel Wolfgang
机构信息
Institut für Anorganische Chemie und Analytische Chemie, Universität Mainz, Duesbergweg 10-14, D-55099, Mainz, Germany.
出版信息
Chem Commun (Camb). 2007 Nov 28(44):4677-9. doi: 10.1039/b707978h. Epub 2007 Aug 28.
DOI:10.1039/b707978h
PMID:17989830
Abstract
Polymer coated superparamagnetic gamma-Fe(2)O(3) nanoparticles were derivatized with a synthetic double-stranded RNA [poly(IC)], a known allosteric activator of the latent (2-5)A synthetase, to separate a single 35 kDa protein from a crude extract which cross reacted with antibodies raised against the sponge enzyme.
摘要
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