Pozharitskaia M M, Makarova O V, Malomud Z P, Kats A G
Stomatologiia (Mosk). 1991 Sep-Oct(5):36-8.
Clinical stomatologic and cytologic studies were carried out in 31 patients with Sjogren's disease, 12 ones with chronic parotitis, and 5 normal subjects. Patients with Sjogren's disease, in contrast to those with chronic parotitis, develop clinically manifest signs of dry exfoliative cheilitis, xerostomia, atrophic changes in the buccal mucosa; this condition is associated with a very high caries intensity and no clinical manifestations of periodontitis or tartar. Elevated leukocyte levels in oral washings and oral fluid of patients with Sjogren's disease and chronic parotitis point to inflammations in the salivary glands, buccal mucosa, and periodontal tissues. Assessment of the leukocyte levels may be used for monitoring the disease course and treatment efficacy. A 3-5-fold enlargement of the deep-layer epitheliocytes, seen on the cytogram of oral washings, is characteristic of patients with Sjogren's disease, in contrast to those with chronic parotitis or normal subjects. A differentiated estimation of the epitheliocyte types in the cytogram of oral washings may be used in the diagnosis of Sjogren's disease along with the criteria suggested before.
对31例干燥综合征患者、12例慢性腮腺炎患者和5名正常受试者进行了临床口腔和细胞学研究。与慢性腮腺炎患者相比,干燥综合征患者临床上会出现明显的干性脱屑性唇炎、口干、颊黏膜萎缩性改变;这种情况与非常高的龋齿发生率相关,且无牙周炎或牙垢的临床表现。干燥综合征和慢性腮腺炎患者口腔冲洗液和口腔液中的白细胞水平升高表明唾液腺、颊黏膜和牙周组织存在炎症。白细胞水平的评估可用于监测疾病进程和治疗效果。与慢性腮腺炎患者或正常受试者相比,干燥综合征患者口腔冲洗液细胞图显示深层上皮细胞增大3 - 5倍。口腔冲洗液细胞图中上皮细胞类型的鉴别估计可与之前提出的标准一起用于干燥综合征的诊断。