Elmore James M, Smith Edwin A, Kirsch Andrew J
Children's Healthcare of Atlanta and Emory University School of Medicine, Atlanta, Georgia, USA.
Urology. 2007 Oct;70(4):803-6. doi: 10.1016/j.urology.2007.07.002.
2-Octyl cyanoacrylate (2-OCA; Dermabond) is a synthetic tissue adhesive that has proven utility in the closure of minor surgical incisions. Recently, we began using this adhesive for skin closure after circumcision and herein report our experience.
A total of 267 patients (mean age 4 years) underwent circumcision (n = 208) or circumcision revision (n = 59) using 2-OCA for skin closure. The circumcision was performed using a sleeve technique in 219 patients and a Gomco clamp in 48. After meticulous hemostasis, the incision was cleansed, and the skin edges were aligned. Two thin layers of 2-OCA were applied to the incision and allowed to dry. Antibiotic ointment was then applied to the glans and penis. The technique was not used if poor skin edge apposition or bleeding was noted after circumcision. The skin closure time using 2-OCA averaged 3 minutes for the first 150 patients and less than 90 seconds for the last 120 patients, reflecting a learning curve associated with application. At a mean follow-up of 13 months (range 2 to 18), three postoperative complications had occurred. The cosmetic outcomes have been subjectively better than those with standard closure using interrupted 5-0 or 6-0 sutures, with no risk of suture tracks or sinuses. Parental satisfaction has been consistently great.
Sutureless circumcision closure using 2-OCA is a safe, fast, and cosmetically appealing alternative to standard interrupted suture reapproximation. These advantages have made it our technique of choice. A direct economic and outcome comparison to sutured repairs is ongoing.
2-辛基氰基丙烯酸酯(2-OCA;皮肤粘合剂)是一种合成组织粘合剂,已被证明可用于闭合小手术切口。最近,我们开始在包皮环切术后使用这种粘合剂进行皮肤闭合,在此报告我们的经验。
共有267例患者(平均年龄4岁)接受了包皮环切术(n = 208)或包皮环切术修复(n = 59),使用2-OCA进行皮肤闭合。219例患者采用袖套技术进行包皮环切术,48例采用Gomco钳。仔细止血后,清洁切口,对齐皮肤边缘。在切口上涂抹两层薄薄的2-OCA,使其干燥。然后在龟头和阴茎上涂抹抗生素软膏。如果包皮环切术后发现皮肤边缘对合不良或出血,则不使用该技术。前150例患者使用2-OCA进行皮肤闭合的平均时间为3分钟,后120例患者少于90秒,这反映了与应用相关的学习曲线。平均随访13个月(范围2至18个月),发生了3例术后并发症。美容效果主观上优于使用间断5-0或6-0缝线的标准闭合方法,没有缝线痕迹或窦道的风险。家长的满意度一直很高。
使用2-OCA进行无缝合包皮环切闭合是一种安全、快速且美观的替代标准间断缝线重新对合的方法。这些优点使其成为我们的首选技术。正在对缝合修复进行直接的经济和结果比较。