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用X射线微量分析法对喉癌患者外周血淋巴细胞中铅、氯和硫含量进行定量测定的试验。

The trial of quantitative determination of the lead, chlorine, and sulfur content in the peripheral blood lymphocytes from patients with cancer of the larynx using the X-ray microanalysis method.

作者信息

Pilch J, Laskawiec J, Gierek T, Lisiewicz J

机构信息

Clinic of Laryngology, Silesian Medical University Academy, Katowice, Poland.

出版信息

Auris Nasus Larynx. 1991;18(3):227-34. doi: 10.1016/s0385-8146(12)80261-6.

DOI:10.1016/s0385-8146(12)80261-6
PMID:1799330
Abstract

Using own modification of X-ray microanalysis method the authors evaluated the lead, chlorine, and sulfur content in the peripheral blood lymphocytes in 20 patients with laryngeal carcinoma in comparison with 20 healthy subjects of the control group. In patients with advanced clinical stages of that carcinoma the elevated lead and chlorine content has been stated in above cells whereas that of sulfur was decreased. According to the authors' opinion above changes reflect functional disturbances of lymphocytes in the patient with laryngeal carcinoma related to the decreased detoxicative properties, the intracellular electrolyte imbalance, and the enzymatic machinery alterations within that cells.

摘要

作者采用自行改良的X射线微量分析法,对20例喉癌患者外周血淋巴细胞中的铅、氯和硫含量进行了评估,并与20名健康对照组受试者进行了比较。在该癌症临床晚期患者中,上述细胞中的铅和氯含量升高,而硫含量降低。作者认为,上述变化反映了喉癌患者淋巴细胞的功能紊乱,这与解毒特性降低、细胞内电解质失衡以及细胞内酶机制改变有关。

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