Zhang Xi Ping, Shi Yan, Zhang Ling
Department of General Surgery, Hangzhou First People's Hospital, Hangzhou, Zhejiang Province, China.
JOP. 2007 Nov 9;8(6):704-14.
This review summarizes the effects and mechanisms of traditional Chinese medicine and herb extracts in treating severe acute pancreatitis. Substances used in traditional Chinese medicine can inhibit pancreatic enzymes and improve microcirculation as well as immunoregulation by blocking the pathological progress of severe acute pancreatitis. Extracts of Chinese herbs not only act on the pancreas, stomach and intestine, but also have markedly therapeutic effects on other viscera damaged as a result of the systemic inflammatory response to acute pancreatitis. Therefore, the application of extracts of Chinese herbs for treating severe acute pancreatitis has significant clinical value and good prospects.
本综述总结了中药及其提取物在治疗重症急性胰腺炎中的作用及机制。中药所用物质可通过阻断重症急性胰腺炎的病理进程来抑制胰酶、改善微循环以及调节免疫。中药提取物不仅作用于胰腺、胃和肠道,对因急性胰腺炎全身炎症反应而受损的其他内脏也有显著治疗作用。因此,应用中药提取物治疗重症急性胰腺炎具有重要的临床价值和良好的前景。