Munzenberger Paul J, Thomas Ron, Bahrainwala Abdul
Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Pharmacy Services, Children's Hospital of Michigan, Detroit Medical Center, Detroit, Michigan 48201, USA.
J Asthma. 2007 Nov;44(9):769-73. doi: 10.1080/02770900701645793.
This study determined retention by children of drug delivery device technique between visits. Patients had asthma requiring the daily use of at least one medication delivery device. Seventy-two patients completed the study; 24 used only the metered dose inhaler (MDI) (group 1), while 48 used the MDI and 1 other device (group 2). Patients or caregivers were initially instructed on and demonstrated the correct use of their medication delivery device(s). At their next visit, they demonstrated their technique for each device. At follow-up, 36% correctly performed all components of the MDI. Group 1 (50%) was higher than group 2 (29%). The percent of correct MDI components for group 1 (84) was also higher than group 2 (78) but not significantly. For both groups and devices, breathing out before inhalation and breath holding was problematic. This study reinforces the need to demonstrate and observe the correct use of inhalation devices at each clinic visit.
本研究确定了儿童在不同就诊期间对给药装置技术的掌握情况。患者患有哮喘，需要每日使用至少一种药物输送装置。72名患者完成了该研究；24名仅使用定量吸入器（MDI）（第1组），而48名使用MDI和另一种装置（第2组）。患者或护理人员最初接受了关于其药物输送装置正确使用方法的指导并进行了演示。在下次就诊时，他们展示了每种装置的使用技巧。在随访时，36%的患者正确完成了MDI的所有操作步骤。第1组（50%）高于第2组（29%）。第1组（84名）正确完成MDI操作步骤的百分比也高于第2组（78名），但差异不显著。对于两组和两种装置而言，吸气前呼气和屏气都存在问题。本研究强调了在每次门诊就诊时演示并观察吸入装置正确使用方法的必要性。
