迟发性步态

Tardive gait.

作者信息

Kuo Sheng-Han, Jankovic Joseph

机构信息

Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, 6550 Fannin, Suite 1801, Houston, TX 77030, United States.

出版信息

Clin Neurol Neurosurg. 2008 Feb;110(2):198-201. doi: 10.1016/j.clineuro.2007.09.013. Epub 2007 Nov 9.

DOI:10.1016/j.clineuro.2007.09.013

PMID:17997030

Abstract

Tardive dyskinesia (TD) is a hyperkinetic movement disorder induced by dopamine receptor blocking drugs (DRBDs). TD typically presents with stereotypy or dystonia, but may also cause akathisia, myoclonus, or tremor. However, no detailed reports of gait abnormalities have been documented. We report three patients exposed to DRBDs who developed "tardive gait" and conclude that gait dysfunction may be part of the TD spectrum.

摘要

迟发性运动障碍（TD）是一种由多巴胺受体阻断药物（DRBDs）诱发的运动亢进性疾病。TD通常表现为刻板动作或肌张力障碍，但也可能导致静坐不能、肌阵挛或震颤。然而，尚未有关于步态异常的详细报道。我们报告了3例接触DRBDs后出现“迟发性步态”的患者，并得出结论，步态功能障碍可能是TD谱的一部分。