Lambiase R E, Paolella L P, Haas R A, Dorfman G S
Department of Diagnostic Imaging, Rhode Island Hospital, Brown University Program in Medicine, Providence 02902.
J Vasc Interv Radiol. 1991 May;2(2):201-8. doi: 10.1016/s1051-0443(91)72283-5.
Six patients with extensive hand and forearm thromboembolic disease were treated by means of intraarterial infusion of urokinase, with good clinical results. Four significant complications occurred, including a possible stroke. Embolization of pericatheter thrombus was a possible etiologic factor in this case. Antegrade brachial artery puncture should be used in the setting of prolonged upper extremity thrombolytic therapy to avoid the cerebral vasculature. Thrombolysis is an effective technique for tissue salvage in cases of inoperable hand thrombosis.
6例患有广泛手部和前臂血栓栓塞性疾病的患者接受了动脉内输注尿激酶治疗，临床效果良好。发生了4例严重并发症，包括1例可能的中风。导管周围血栓形成栓塞可能是该病例的病因。在进行长时间上肢溶栓治疗时应采用肱动脉顺行穿刺，以避免脑血管系统受到影响。对于无法手术的手部血栓形成病例，溶栓是一种有效的组织挽救技术。
